Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1E | P49674 | 14/20 | 0.47 |
| ▸ | NAMPT | P43490 | 2/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14368453 | 0.97 | CSNK1E (0.45) | CSNK1ENAMPTEPHX2CHRNA7 | |
| SCHEMBL13964269 | 0.91 | NAMPT (0.49) | CSNK1ENAMPT | |
| SCHEMBL13963964 | 0.88 | CSNK1E (0.49) | CSNK1ENAMPT | |
| SCHEMBL14368383 | 0.87 | NAMPT (0.46) | CSNK1ENAMPT | |
| SCHEMBL13964334 | 0.87 | CSNK1E (0.50) | CSNK1ENAMPT | |
| SCHEMBL14368398 | 0.87 | CSNK1E (0.52) | CSNK1E | |
| SCHEMBL4041559 | 0.86 | CSNK1E (0.49) | CSNK1E | |
| SCHEMBL14368388 | 0.85 | CSNK1E (0.53) | CSNK1E | |
| SCHEMBL13963918 | 0.85 | CSNK1E (0.52) | CSNK1ENAMPT | |
| SCHEMBL14368412 | 0.85 | CSNK1E (0.51) | CSNK1E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070238734-A1 | JNK INHIBITORS | SANOLI-AVENTIS (FR) | 2007-10-11 | — | — | US | disclosed |
| US-20070238734-A1 | JNK INHIBITORS | SANOLI-AVENTIS (FR) | 2007-10-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070238734-A1 | JNK INHIBITORS | MAP3K7, MAPKAPK2, MAPK7 | CSNK1E 136/4885NAMPT 2464/4885EPHX2 3367/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.