Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2338626 | 1.00 | CCR5 (0.56) | CCR5RIPK1 | |
| Hydrochloric Acid SCHEMBL2334551 | 0.99 | CCR5 (0.55) | CCR5RIPK1 | |
| SCHEMBL14371061 | 0.95 | CCR5 (0.60) | CCR5RIPK1 | |
| SCHEMBL14371065 | 0.95 | CCR5 (0.50) | CCR5RIPK1 | |
| SCHEMBL2338582 | 0.95 | CCR5 (0.60) | CCR5RIPK1 | |
| SCHEMBL2339380 | 0.95 | CCR5 (0.50) | CCR5RIPK1 | |
| Hydrochloric Acid SCHEMBL2343459 | 0.94 | CCR5 (0.49) | CCR5RIPK1 | |
| Hydrochloric Acid SCHEMBL2341269 | 0.94 | CCR5 (0.59) | CCR5RIPK1 | |
| SCHEMBL2339275 | 0.93 | CCR5 (0.60) | CCR5RIPK1 | |
| SCHEMBL2335077 | 0.93 | CCR5 (0.61) | CCR5RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7288548-B2 | Spiro compounds and methods for the modulation of chemokine receptor activity | VIROCHEM PHARMA, INC. (CA) | 2007-10-30 | — | — | US | disclosed |
| US-7288548-B2 | Spiro compounds and methods for the modulation of chemokine receptor activity | VIROCHEM PHARMA, INC. (CA) | 2007-10-30 | — | — | US | disclosed |