SCHEMBL14371925

SCHEMBL14371925

CCCCCC[Si]1(CCCCCC)c2cc(B3OC(C)(C)C(C)(C)O3)ccc2-c2ccc(B3OC(C)(C)C(C)(C)O3)cc21

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LIPG Q9Y5X9 14/20 0.54
LPL P06858 13/20 0.54
F11 P03951 1/20 0.34
ESR2 Q92731 1/20 0.32
CA1 P00915 2/20 0.32
CA2 P00918 2/20 0.32
CA9 Q16790 2/20 0.32
CA12 O43570 1/20 0.32
CA3 P07451 1/20 0.32
CA4 P22748 1/20 0.32
CA6 P23280 1/20 0.32
CA5A P35218 1/20 0.32
CA7 P43166 1/20 0.32
CA14 Q9ULX7 1/20 0.32
CA5B Q9Y2D0 1/20 0.32
RORA P35398 1/20 0.32
RORC P51449 1/20 0.32
RORB Q92753 1/20 0.32
PRMT5 O14744 1/20 0.31
WDR77 Q9BQA1 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15257233 1.00 LIPG (0.54) LIPGLPLF11ESR2CA1
SCHEMBL14790083 1.00 LIPG (0.54) LIPGLPLF11ESR2CA1
SCHEMBL12131317 1.00 LIPG (0.54) LIPGLPLF11ESR2CA1
SCHEMBL14371943 0.89 LIPG (0.54) LIPGLPLF11ESR2CA1
SCHEMBL15698977 0.78 LIPG (0.45) LIPGLPLF11ESR2
SCHEMBL2949873 0.77 LIPG (0.64) LIPGLPLF11ESR2
SCHEMBL14816705 0.76 LIPG (0.44) LIPGLPLF11ESR2CA1
SCHEMBL2956994 0.75 LIPG (0.54) LIPGLPLF11ESR2CA1
SCHEMBL18437010 0.75 LIPG (0.54) LIPGLPLF11ESR2CA1
SCHEMBL21944334 0.75 LIPG (0.54) LIPGLPLF11ESR2CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11183648-B2 Polymers, their preparation and uses CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2021-11-23 US disclosed
US-20160343961-A1 POLYMERS, THEIR PREPARATION AND USES CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2016-11-24 US disclosed
US-20160343961-A1 POLYMERS, THEIR PREPARATION AND USES CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2016-11-24 US disclosed
US-9419233-B2 Polymers, their preparation and uses CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2016-08-16 US disclosed
US-9419233-B2 Polymers, their preparation and uses CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2016-08-16 US disclosed
EP-2578592-B1 QUINOID SILAFLUORENE ORGANIC SEMICONDUCTOR MATERIAL, PREPARATION METHOD AND USE THEREOF OCEAN S KING LIGHTING SCIENCE&TECHNOLOGY CO LTD (CN) 2016-07-13 EP disclosed
US-8481754-B2 Quinoid silafluorene organic semiconductor material, preparation method and use thereof OCEAN'S KING LIGHTING SCIENCE & TECHNOLOGY CO., LTD. (CN) 2013-07-09 US disclosed
EP-2578592-A1 QUINOID SILAFLUORENE ORGANIC SEMICONDUCTOR MATERIAL, PREPARATION METHOD AND USE THEREOF Ocean's King Lighting Science&Technology Co., Ltd. (CN) 2013-04-10 EP disclosed
US-20130072693-A1 QUINOID SILAFLUORENE ORGANIC SEMICONDUCTOR MATERIAL, PREPARATION METHOD AND USE THEREOF OCEAN'S KING LIGHTING SCIENCE & TECHNOLOGY CO., LTD. (CN) 2013-03-21 US disclosed
US-20070248839-A1 Dibenzosilol Polymers, Their Preparation and Uses CAMBRIDGE ENTERPRISE LIMITED (GB) 2007-10-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160343961-A1 POLYMERS, THEIR PREPARATION AND USES PARG, PARP1, PCBP1 LIPG 4220/4885LPL 4132/4885F11 908/4885
US-11183648-B2 Polymers, their preparation and uses PARG, PARP1, PCBP1 LIPG 4220/4885LPL 4132/4885F11 908/4885
US-20130072693-A1 QUINOID SILAFLUORENE ORGANIC SEMICONDUCTOR MATERIAL, PREPARATION METHOD AND USE THEREOF RPS4Y1, OR10J3, C5 LIPG 4800/4885LPL 4849/4885F11 65/4885
US-20070248839-A1 Dibenzosilol Polymers, Their Preparation and Uses PARG, PCBP1, RAD54L LIPG 3804/4885LPL 3537/4885F11 1383/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.