Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | ACP3 | P15309 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16376975 | 0.85 | ALDH1A1 (0.49) | ESR1ACP3ALDH1A1HPGDTSHR | |
| SCHEMBL28224851 | 0.83 | ESR1 (0.37) | ESR1ACP3ALDH1A1HPGDACHE | |
| SCHEMBL29388433 | 0.82 | ALDH1A1 (0.50) | ESR1ACP3ALDH1A1HPGDTSHR | |
| SCHEMBL22917035 | 0.82 | ESR1 (0.46) | ESR1ACP3ALDH1A1HPGDTSHR | |
| SCHEMBL2206363 | 0.82 | SRC (0.50) | ESR1ACP3ALDH1A1HPGDTSHR | |
| SCHEMBL30136352 | 0.82 | SRC (0.50) | ESR1ACP3ALDH1A1HPGDTSHR | |
| SCHEMBL26229977 | 0.80 | ESR1 (0.39) | ESR1ACP3ALDH1A1HPGDTSHR | |
| SCHEMBL28885018 | 0.80 | ALDH1A1 (0.37) | ESR1ACP3ALDH1A1HPGDMEN1 | |
| SCHEMBL21552683 | 0.80 | ESR1 (0.45) | ESR1ACP3ALDH1A1HPGDTSHR | |
| SCHEMBL124623 | 0.80 | ESR1 (0.45) | ESR1ACP3ALDH1A1HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070249634-A1 | Triazolopyrimidine Compounds and Use Thereof for Controlling Harmful Fungi | BASF AKTIENGESELLSCHAFT (DE) | 2007-10-25 | — | — | US | disclosed |
| US-20070238744-A1 | Use of 6-(2-Tolyl)-Triazolopyrimidines as Fungicides, Novel 6-(2-Tolyl)-Triazolopyrimidines, Method for the Production Thereof, Used There of for Controlling Harmful Fungi, and Agents Containing the Same | BASF AKTIENGESELLSCHAFT (DE) | 2007-10-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070249634-A1 | Triazolopyrimidine Compounds and Use Thereof for Controlling Harmful Fungi | CBR3, CBR1, NR2C2 | ESR1 1703/4885ACP3 4028/4885ALDH1A1 1667/4885 |
| US-20070238744-A1 | Use of 6-(2-Tolyl)-Triazolopyrimidines as Fungicides, Novel 6-(2-Tolyl)-Triazolopyrimidines, Method for the Production Thereof, Used There of for Controlling Harmful Fungi, and Agents Containing the Same | DPM1, CYP4X1, CBR1 | ESR1 4748/4885ACP3 4582/4885ALDH1A1 1183/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.