Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 4/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CES2 | O00748 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5077504 | 0.80 | CES1 (0.43) | CES1NPSR1RAB9ANPC1CA2 | |
| SCHEMBL9682227 | 0.77 | CA2 (0.42) | CES1NPSR1CA2CA4CA5A | |
| SCHEMBL14372102 | 0.77 | CES1 (0.41) | CES1NPSR1RAB9ANPC1CA2 | |
| SCHEMBL9736806 | 0.69 | CES1 (0.45) | CES1RAB9ANPC1CA2CA4 | |
| SCHEMBL7358801 | 0.69 | TSHR (0.45) | CES1RAB9ANPC1PTPN1KMT2A | |
| SCHEMBL10453294 | 0.69 | TSHR (0.43) | RAB9ANPC1MEN1KMT2AALDH1A1 | |
| SCHEMBL1436220 | 0.69 | CES1 (0.60) | CES1RAB9ACA2CA4CA5A | |
| SCHEMBL28837173 | 0.68 | CA2 (0.40) | NPSR1CA2CA4CA5AUSP2 | |
| Trifluoroacetic Acid SCHEMBL8535334 | 0.67 | CES1 (0.52) | CES1NPSR1RAB9ANPC1CA2 | |
| Water SCHEMBL3137210 | 0.67 | CES1 (0.58) | CES1RAB9ACA2CA4CA5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070244261-A1 | Polyolefin Graft Copolymer, Composition and Method for Producing Same | KANEKA CORPORATION (JP) | 2007-10-18 | — | — | US | disclosed |
| US-20070244261-A1 | Polyolefin Graft Copolymer, Composition and Method for Producing Same | KANEKA CORPORATION (JP) | 2007-10-18 | — | — | US | disclosed |
| EP-1762579-A1 | POLYOLEFIN GRAFT COPOLYMER, COMPOSITION AND METHOD FOR PRODUCING SAME | Kaneka Corporation (JP) | 2007-03-14 | — | — | EP | disclosed |