Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14372255 | 0.95 | POLB (0.38) | MMP2MMP3MMP9MMP13 | |
| SCHEMBL9377590 | 0.79 | KCNH2 (0.39) | KCNH2SCN5AMMP2MMP3MMP9 | |
| SCHEMBL12013041 | 0.76 | BRD4 (0.38) | — | |
| SCHEMBL3521417 | 0.75 | TP53 (0.43) | KCNH2SCN5AMMP2MMP3MMP9 | |
| SCHEMBL3524929 | 0.75 | KCNH2 (0.42) | KCNH2SCN5A | |
| SCHEMBL9496530 | 0.74 | HTT (0.38) | KCNH2SCN5AMMP2MMP3MMP9 | |
| SCHEMBL9377308 | 0.74 | MMP2 (0.38) | KCNH2SCN5AMMP2MMP3MMP9 | |
| SCHEMBL3524695 | 0.73 | KCNH2 (0.35) | KCNH2SCN5AMMP2MMP3MMP9 | |
| SCHEMBL9378019 | 0.73 | MMP2 (0.39) | KCNH2SCN5AMMP2MMP3MMP9 | |
| SCHEMBL9485950 | 0.73 | MMP2 (0.39) | MMP2MMP3MMP9MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7279444-B2 | Substituted benzoylpyrazoles | BAYER CROPSCIENCE GMBH (DE) | 2007-10-09 | — | — | US | disclosed |
| US-7279444-B2 | Substituted benzoylpyrazoles | BAYER CROPSCIENCE GMBH (DE) | 2007-10-09 | — | — | US | disclosed |