Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK2 | P49760 | 1/20 | 0.62 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.62 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.62 |
| ▸ | CXCR3 | P49682 | 13/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | BRSK1 | Q8TDC3 | 1/20 | 0.51 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CRHBP | P24387 | 1/20 | 0.45 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14373625 | 0.91 | CXCR3 (0.57) | CLK2DYRK1ACLK4CXCR3MEN1 | |
| SCHEMBL14373585 | 0.91 | CLK2 (0.74) | CLK2DYRK1ACLK4CXCR3MEN1 | |
| SCHEMBL14373614 | 0.90 | CLK2 (0.58) | CLK2DYRK1ACLK4CXCR3MEN1 | |
| SCHEMBL14373609 | 0.87 | CXCR3 (0.72) | CXCR3MEN1KMT2ANPC1RAB9A | |
| SCHEMBL14373449 | 0.86 | CXCR3 (0.63) | CLK2DYRK1ACLK4CXCR3BRSK1 | |
| SCHEMBL14373589 | 0.86 | CLK2 (0.83) | CLK2DYRK1ACLK4CXCR3MEN1 | |
| SCHEMBL14373631 | 0.85 | CXCR3 (0.55) | CLK2DYRK1ACLK4CXCR3MEN1 | |
| SCHEMBL14373347 | 0.84 | CXCR3 (0.76) | CLK2DYRK1ACLK4CXCR3MEN1 | |
| SCHEMBL14373441 | 0.83 | CXCR3 (0.70) | CLK2DYRK1ACLK4CXCR3BRSK1 | |
| SCHEMBL14373619 | 0.82 | CLK2 (0.60) | CLK2DYRK1ACLK4CXCR3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070232673-A1 | 2-Imino-benzimidazoles | ABBOTT LABORATORIES | 2007-10-04 | — | — | US | disclosed |
| US-20070232673-A1 | 2-Imino-benzimidazoles | ABBOTT LABORATORIES | 2007-10-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070232673-A1 | 2-Imino-benzimidazoles | CYP2C19, UGT2B7, UGT2B17 | CLK2 1827/4885DYRK1A 4540/4885CLK4 3424/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.