Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 19/20 | 0.60 |
| ▸ | DPP8 | Q6V1X1 | 7/20 | 0.49 |
| ▸ | DPP7 | Q9UHL4 | 4/20 | 0.49 |
| ▸ | PREP | P48147 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL664911 | 1.00 | DPP4 (0.60) | DPP4DPP8DPP7PREP | |
| SCHEMBL1437709 | 0.88 | DPP4 (0.63) | DPP4DPP8DPP7 | |
| SCHEMBL665486 | 0.88 | DPP4 (0.63) | DPP4DPP8DPP7 | |
| SCHEMBL665641 | 0.86 | DPP4 (0.56) | DPP4DPP8DPP7PREP | |
| SCHEMBL664983 | 0.86 | DPP4 (0.59) | DPP4DPP8DPP7 | |
| SCHEMBL4606934 | 0.86 | DPP4 (0.59) | DPP4DPP8DPP7 | |
| SCHEMBL6335491 | 0.84 | DPP4 (0.44) | DPP4DPP7PREP | |
| SCHEMBL665359 | 0.84 | DPP4 (0.54) | DPP4DPP8DPP7PREP | |
| SCHEMBL4606161 | 0.82 | ALDH1A1 (0.41) | DPP4 | |
| SCHEMBL6335492 | 0.80 | PREP (0.46) | DPP4DPP8PREP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1441719-B1 | N-SUBSTITUTED PYRROLIDIN DERIVATIVES AS DIPEPTIDYL PEPTIDASE IV INHIBITORS | HOFFMANN LA ROCHE (CH) | 2011-03-30 | — | — | EP | disclosed |