SCHEMBL14373622

SCHEMBL14373622

O=COc1ccc2cc(OC(=O)c3ccc(O)cc3)ccc2c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 9/20 0.53
▸ MEN1 O00255 6/20 0.53
▸ MAPT P10636 2/20 0.53
▸ TDP1 Q9NUW8 1/20 0.53
▸ ESR1 P03372 4/20 0.48
▸ CASP3 P42574 2/20 0.47
▸ SENP8 Q96LD8 2/20 0.47
▸ SENP7 Q9BQF6 2/20 0.47
▸ SENP6 Q9GZR1 2/20 0.47
▸ NPC1 O15118 1/20 0.46
▸ HGFAC Q04756 2/20 0.44
▸ TMPRSS2 O15393 1/20 0.44
▸ MLNR O43193 1/20 0.44
▸ ALDH1A1 P00352 1/20 0.44
▸ F2 P00734 1/20 0.44
▸ C1R P00736 1/20 0.44
▸ F10 P00742 1/20 0.44
▸ PLG P00747 1/20 0.44
▸ F12 P00748 1/20 0.44
▸ LMNA P02545 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL777824 0.88 KMT2A (0.65) KMT2AMEN1MAPTTDP1ESR1
SCHEMBL14373620 0.87 HSD17B10 (0.47) KMT2AMEN1MAPTESR1HGFAC
SCHEMBL8756308 0.85 KMT2A (0.61) KMT2AMEN1MAPTTDP1ESR1
SCHEMBL11297653 0.85 KMT2A (0.61) KMT2AMEN1MAPTTDP1ESR1
SCHEMBL12922696 0.83 KMT2A (0.51) KMT2AMEN1MAPTTDP1ESR1
SCHEMBL8851038 0.82 KMT2A (0.77) KMT2AMEN1MAPTTDP1ESR1
SCHEMBL14679430 0.81 KMT2A (0.63) KMT2AMEN1MAPTTDP1ESR1
SCHEMBL9793342 0.81 KMT2A (0.60) KMT2AMEN1MAPTTDP1ESR1
SCHEMBL14373617 0.81 KMT2A (0.43) KMT2AMEN1MAPTESR1CASP3
SCHEMBL26082823 0.80 MAPT (0.41) KMT2AMEN1MAPTESR1CASP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070298191-A1 Optical Film SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-12-27 — — US disclosed
US-20070085334-A1 Indicator for indicating authenticity DAI NIPPON PRINTING CO., LTD. (JP) 2007-04-19 — — US disclosed
US-7158299-B2 Projection screen and projection system comprising the same DAI NIPPON PRINTING CO., LTD. (JP) 2007-01-02 — — US disclosed
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