SCHEMBL143737

SCHEMBL143737

Cc1ccccc1C(C)N

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.52
CYP3A4 P08684 3/20 0.46
CYP1A2 P05177 2/20 0.46
CYP2D6 P10635 2/20 0.46
NFKB1 P19838 2/20 0.46
PNMT P11086 1/20 0.46
TSHR P16473 2/20 0.45
ACHE P22303 1/20 0.45
LMNA P02545 3/20 0.45
ALDH1A1 P00352 1/20 0.45
GLA P06280 1/20 0.45
MAOA P21397 2/20 0.42
MAOB P27338 2/20 0.42
TDP1 Q9NUW8 1/20 0.40
ACP3 P15309 1/20 0.39
ADRA2A P08913 1/20 0.39
ADRA2C P18825 1/20 0.39
HIF1A Q16665 1/20 0.39
KDM4E B2RXH2 1/20 0.39
SCN4A P35499 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2332685 1.00 ESR1 (0.52) ESR1CYP3A4CYP1A2CYP2D6NFKB1
SCHEMBL3867592 1.00 ESR1 (0.52) ESR1CYP3A4CYP1A2CYP2D6NFKB1
Hydrochloric Acid SCHEMBL4938432 0.97 ESR1 (0.50) ESR1CYP3A4CYP1A2CYP2D6NFKB1
Hydrochloric Acid SCHEMBL14121220 0.97 ESR1 (0.50) ESR1CYP3A4CYP1A2CYP2D6NFKB1
Hydrochloric Acid SCHEMBL14157216 0.97 ESR1 (0.50) ESR1CYP3A4CYP1A2CYP2D6NFKB1
SCHEMBL11082805 0.85 ESR1 (0.48) ESR1CYP3A4CYP1A2CYP2D6NFKB1
SCHEMBL25569190 0.83 KDM4E (0.56) ESR1CYP2D6NFKB1TSHRACHE
SCHEMBL5051416 0.83 KDM4E (0.56) ESR1CYP2D6NFKB1TSHRACHE
SCHEMBL30678522 0.83 CYP2D6 (0.54) CYP3A4CYP1A2CYP2D6NFKB1PNMT
SCHEMBL14395925 0.83 CYP2D6 (0.54) CYP3A4CYP1A2CYP2D6NFKB1PNMT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 186 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119923169-A Method for improving circularly polarized light detection performance of perovskite film through achiral cations 复旦大学 2025-05-02 CN claimed
CN-118324680-A Synthesis method of (alpha S, 3S) -alpha-amino-2-oxo-3-pyrrolidine propionamide hydrochloride 宁波酶赛生物工程有限公司 2024-07-12 CN claimed
CN-115819221-B Preparation method of (R) -2-hydroxymethyl propionic acid and (S) -2-hydroxymethyl propionic acid 上海馨远医药科技有限公司 2024-05-10 CN claimed
CN-117082953-A Optoelectronic device and method for producing the same 天合光能股份有限公司 2023-11-17 CN claimed
CN-115819221-A Preparation method of (R) -2-hydroxymethyl propionic acid and (S) -2-hydroxymethyl propionic acid 上海馨远医药科技有限公司 2023-03-21 CN claimed
WO-2014001075-A1 PROCESS FOR RACEMIZING OPTICALLY ACTIVE ARYLALKYLAMINES BASF SE (DE) 2014-01-03 WO claimed
US-8435963-B2 Weight loss compositions and uses thereof ENERGY BEVERAGES LLC 2013-05-07 US claimed
EP-2254890-A1 PROCESS FOR THE DIASTEREOISOMERIC RESOLUTION OF 5-METHYLTETRAHYDROFOLIC ACID Gnosis S.p.A. (IT) 2010-12-01 EP claimed
US-20100081626-A1 WEIGHT LOSS COMPOSITIONS AND USES THEREOF ENERGY BEVERAGES LLC 2010-04-01 US claimed
WO-2009103333-A1 PROCESS FOR THE DIASTEREOISOMERIC RESOLUTION OF 5-METHYLTETRAHYDROFOLIC ACID GNOSIS S.P.A. (IT) 2009-08-27 WO claimed
CN-119923380-A N-substituted phenylalkylamines and their use as therapeutic agents 亚历山大舒尔金研究所有限公司 2025-05-02 CN disclosed
CN-118465006-A Metal ion conduction MOFs-based chemical sensor for detecting methylaniline drugs and preparation method thereof 同济大学 2024-08-09 CN disclosed
CN-118324680-A Synthesis method of (alpha S, 3S) -alpha-amino-2-oxo-3-pyrrolidine propionamide hydrochloride 宁波酶赛生物工程有限公司 2024-07-12 CN disclosed
CN-115819221-B Preparation method of (R) -2-hydroxymethyl propionic acid and (S) -2-hydroxymethyl propionic acid 上海馨远医药科技有限公司 2024-05-10 CN disclosed
CN-117623935-A Method for preparing amine compound by reductive amination of molecular sieve-based metal catalyst 浙江大学 2024-03-01 CN disclosed
US-5686458-A Quinazoline deriviates for treating peptic ulcer YUHAN CORPORATION (KR) 1997-11-11 US disclosed
US-5672574-A Stabilizers for organic materials CIBA-GEIGY CORPORATION (US) 1997-09-30 US disclosed
EP-0677049-A1 QUINAZOLINE DERIVATIVES YUHAN CORPORATION, LTD. (KR) 1995-10-18 EP disclosed
WO-1994014795-A1 QUINAZOLINE DERIVATIVES YUHAN CORPORATION (KR) 1994-07-07 WO disclosed
US-4863938-A Pyridine derivatives and their use as nootropic agents CIBA-GEIGY CORPORATION (US) 1989-09-05 US disclosed