Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.46 |
| ▸ | PNMT | P11086 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ACP3 | P15309 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | SCN4A | P35499 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL143737 | 1.00 | ESR1 (0.52) | ESR1CYP3A4CYP1A2CYP2D6NFKB1 | |
| SCHEMBL3867592 | 1.00 | ESR1 (0.52) | ESR1CYP3A4CYP1A2CYP2D6NFKB1 | |
| Hydrochloric Acid SCHEMBL4938432 | 0.97 | ESR1 (0.50) | ESR1CYP3A4CYP1A2CYP2D6NFKB1 | |
| Hydrochloric Acid SCHEMBL14121220 | 0.97 | ESR1 (0.50) | ESR1CYP3A4CYP1A2CYP2D6NFKB1 | |
| Hydrochloric Acid SCHEMBL14157216 | 0.97 | ESR1 (0.50) | ESR1CYP3A4CYP1A2CYP2D6NFKB1 | |
| SCHEMBL11082805 | 0.85 | ESR1 (0.48) | ESR1CYP3A4CYP1A2CYP2D6NFKB1 | |
| SCHEMBL25569190 | 0.83 | KDM4E (0.56) | ESR1CYP2D6NFKB1TSHRACHE | |
| SCHEMBL5051416 | 0.83 | KDM4E (0.56) | ESR1CYP2D6NFKB1TSHRACHE | |
| SCHEMBL30678522 | 0.83 | CYP2D6 (0.54) | CYP3A4CYP1A2CYP2D6NFKB1PNMT | |
| SCHEMBL14395925 | 0.83 | CYP2D6 (0.54) | CYP3A4CYP1A2CYP2D6NFKB1PNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220064111-A1 | ENANTIOSELECTIVE SYNTHESIS OF BRIVARACETAM AND INTERMEDIATES THEREOF | CLININVENT RESEARCH PVT. LTD. (IN) | 2022-03-03 | — | — | US | claimed |
| US-20250145561-A1 | 4-SUBSTITUTED-PHENYL ACETAMIDES AND ARYLUREAS AS AGONISTS FOR THE ORPHAN RECEPTOR GPR88 | RESEARCH TRIANGLE INSTITUTE (US) | 2025-05-08 | — | — | US | disclosed |
| EP-4469431-A1 | 4-SUBSTITUTED-PHENYL ACETAMIDES AND ARYLUREAS AS AGONISTS FOR THE ORPHAN RECEPTOR GPR88 | Research Triangle Institute (US) | 2024-12-04 | — | — | EP | disclosed |
| CN-118541348-A | 4-Substituted-phenylacetamides and aryl ureas as agonists of the orphan receptor GPR88 | 研究三角协会 | 2024-08-23 | — | — | CN | disclosed |
| EP-3365334-B1 | BENZOLACTAM COMPOUNDS AS PROTEIN KINASE INHIBITORS | OTSUKA PHARMA CO LTD (JP) | 2024-07-17 | — | — | EP | disclosed |
| CN-114438049-B | Amine dehydrogenase and encoding nucleic acid and application thereof | 河北工业大学 | 2023-09-15 | — | — | CN | disclosed |
| US-20230278959-A1 | Synthesis of Optically Active Indoline Derivatives Via Ruthenium(II)-Catalyzed Enantioselective C-H Functionalization | MISSISSIPPI STATE UNIVERSITY | 2023-09-07 | — | — | US | disclosed |
| US-20230278959-A1 | Synthesis of Optically Active Indoline Derivatives Via Ruthenium(II)-Catalyzed Enantioselective C-H Functionalization | MISSISSIPPI STATE UNIVERSITY | 2023-09-07 | — | — | US | disclosed |
| WO-2023146816-A1 | 4-SUBSTITUTED-PHENYL ACETAMIDES AND ARYLUREAS AS AGONISTS FOR THE ORPHAN RECEPTOR GPR88 | RESEARCH TRIANGLE INSTITUTE (US) | 2023-08-03 | — | — | WO | disclosed |
| CN-114438049-A | Amine dehydrogenase and coding nucleic acid and application thereof | 河北工业大学 | 2022-05-06 | — | — | CN | disclosed |
| US-20030236435-A1 | Synthesis of 2-alkylcysteine via substituted thiazoline ester | GENZYME CORPORATION | 2003-12-25 | — | — | US | disclosed |
| US-20030236404-A1 | Synthesis of 2-alkylcysteine via phase transfer catalysis | GENZYME CORPORATION | 2003-12-25 | — | — | US | disclosed |
| US-20030236434-A1 | Synthesis of 2-alkylcysteine via substituted thiazoline amide | GENZYME CORPORATION (US) | 2003-12-25 | — | — | US | disclosed |
| US-20030229231-A1 | Synthesis of 2-alkylcysteine | GENZYME CORPORATION | 2003-12-11 | — | — | US | disclosed |
| US-20030225287-A1 | Synthesis of chiral 2-alkyl amino acids | GENZYME CORPORATION | 2003-12-04 | — | — | US | disclosed |
| EP-1211254-A1 | PROCESS FOR THE PREPARATION OF BENZOXAZINE DERIVATIVES AND INTERMEDIATES THEREFOR | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2002-06-05 | — | — | EP | disclosed |
| US-5510519-A | OPTICAL RESOLUTION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1996-04-23 | — | — | US | disclosed |
| EP-0508307-B1 | Optically active secondary amine compound; process for producing optically active secondary amine compound and process for producing optically active carboxylic acid by using said compound | SUMITOMO CHEMICAL CO (JP) | 1995-11-29 | — | — | EP | disclosed |
| US-5298660-A | Compound containing an assymetrical carbon atom | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1994-03-29 | — | — | US | disclosed |
| EP-0508307-A2 | Optically active secondary amine compound; process for producing optically active secondary amine compound and process for producing optically active carboxylic acid by using said compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1992-10-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030225287-A1 | Synthesis of chiral 2-alkyl amino acids | FTH1, CISD2, PTMS | ESR1 4183/4885CYP3A4 2754/4885CYP1A2 3833/4885 |
| US-20030236404-A1 | Synthesis of 2-alkylcysteine via phase transfer catalysis | DIMT1, ICMT, CNDP2 | ESR1 4055/4885CYP3A4 2320/4885CYP1A2 3311/4885 |
| US-20230278959-A1 | Synthesis of Optically Active Indoline Derivatives Via Ruthenium(II)-Catalyzed Enantioselective C-H Functionalization | INMT, IDO2, WEE2 | ESR1 1486/4885CYP3A4 311/4885CYP1A2 150/4885 |
| US-20030236435-A1 | Synthesis of 2-alkylcysteine via substituted thiazoline ester | FTH1, TFRC, CNDP2 | ESR1 2636/4885CYP3A4 2981/4885CYP1A2 3561/4885 |
| US-20220064111-A1 | ENANTIOSELECTIVE SYNTHESIS OF BRIVARACETAM AND INTERMEDIATES THEREOF | CYP2B6, CYP3A4, CYP2C19 | ESR1 1643/4885CYP3A4 2/4885CYP1A2 21/4885 |
| US-20030229231-A1 | Synthesis of 2-alkylcysteine | FTH1, CISD2, CNDP2 | ESR1 4470/4885CYP3A4 3118/4885CYP1A2 4001/4885 |
| US-20030236434-A1 | Synthesis of 2-alkylcysteine via substituted thiazoline amide | CNDP2, FTH1, PTMS | ESR1 3601/4885CYP3A4 3961/4885CYP1A2 4353/4885 |
| US-20250145561-A1 | 4-SUBSTITUTED-PHENYL ACETAMIDES AND ARYLUREAS AS AGONISTS FOR THE ORPHAN RECEPTOR GPR88 | GPR88, GPR84, GPR139 | ESR1 841/4885CYP3A4 1510/4885CYP1A2 919/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.