Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 5/20 | 0.80 |
| ▸ | GPBAR1 | Q8TDU6 | 5/20 | 0.80 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.80 |
| ▸ | RORC | P51449 | 2/20 | 0.80 |
| ▸ | GLI1 | P08151 | 2/20 | 0.80 |
| ▸ | LMNA | P02545 | 2/20 | 0.80 |
| ▸ | ALB | P02768 | 2/20 | 0.80 |
| ▸ | USP2 | O75604 | 1/20 | 0.80 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.80 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.80 |
| ▸ | POLB | P06746 | 1/20 | 0.80 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.80 |
| ▸ | DPP4 | P27487 | 1/20 | 0.80 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.80 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.80 |
| ▸ | RELA | Q04206 | 1/20 | 0.71 |
| ▸ | PRKCG | P05129 | 1/20 | 0.71 |
| ▸ | CES2 | O00748 | 2/20 | 0.70 |
| ▸ | CES1 | P23141 | 2/20 | 0.70 |
| ▸ | F3 | P13726 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14693097 | 1.00 | NT5E (0.80) | NT5EGPBAR1PTPN1RORCGLI1 | |
| SCHEMBL13259806 | 1.00 | NT5E (0.80) | NT5EGPBAR1PTPN1RORCGLI1 | |
| SCHEMBL13285629 | 1.00 | NT5E (0.80) | NT5EGPBAR1PTPN1RORCGLI1 | |
| SCHEMBL13259775 | 1.00 | NT5E (0.80) | NT5EGPBAR1PTPN1RORCGLI1 | |
| SCHEMBL14398791 | 1.00 | NT5E (0.80) | NT5EGPBAR1PTPN1RORCGLI1 | |
| SCHEMBL5452263 | 1.00 | NT5E (0.80) | NT5EGPBAR1PTPN1RORCGLI1 | |
| SCHEMBL13285520 | 1.00 | NT5E (0.80) | NT5EGPBAR1PTPN1RORCGLI1 | |
| SCHEMBL13908797 | 0.93 | RORC (0.73) | NT5EGPBAR1PTPN1RORCGLI1 | |
| SCHEMBL17128775 | 0.89 | RORC (0.71) | NT5EGPBAR1PTPN1RORCGLI1 | |
| SCHEMBL17128777 | 0.89 | RORC (0.71) | NT5EGPBAR1PTPN1RORCGLI1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070232577-A1 | Synthetic pentacyclic triterpenoids and derivatives of betulinic acid and betulin | ADVANCED LIFE SCIENCES, INC. (US) | 2007-10-04 | — | — | US | disclosed |
| US-20070232577-A1 | Synthetic pentacyclic triterpenoids and derivatives of betulinic acid and betulin | ADVANCED LIFE SCIENCES, INC. (US) | 2007-10-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070232577-A1 | Synthetic pentacyclic triterpenoids and derivatives of betulinic acid and betulin | BET1, PGGT1B, BRCA1 | NT5E 3553/4885GPBAR1 225/4885PTPN1 4086/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.