SCHEMBL14374580

COc1ccc(N=Nc2c(S(=O)(=O)O)cc3cc(SOOO)c(N=Nc4cc(S(=O)(=O)O)c5cc(SOOO)c(N=Nc6ccc7c(O)c(N=Nc8ccccc8S(=O)(=O)O)c(SOOO)cc7c6)c(O)c5c4N)cc3c2O)c(SOOO)c1

nearest known ligand 0.44

Predicted protein targets (top 7)

	gene	UniProt	supporting neighbours	confidence
▸	PHLPP2	Q6ZVD8	2/20	0.44

▸	ENPP2	Q13822	11/20	0.39

▸	PTPN11	Q06124	1/20	0.38

▸	SLC7A11	Q9UPY5	2/20	0.36

▸	CD40	P25942	1/20	0.36

▸	CD40LG	P29965	1/20	0.36

▸	CYP1A2	P05177	2/20	0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL14374888	0.93	PHLPP2 (0.42)	PHLPP2ENPP2PTPN11SLC7A11CD40
SCHEMBL14374683	0.93	PHLPP2 (0.42)	PHLPP2ENPP2PTPN11SLC7A11CD40
SCHEMBL14374581	0.92	PHLPP2 (0.44)	PHLPP2ENPP2PTPN11SLC7A11CD40
SCHEMBL14374736	0.91	PHLPP2 (0.41)	PHLPP2ENPP2PTPN11SLC7A11CD40
SCHEMBL13388581	0.90	ENPP2 (0.47)	PHLPP2ENPP2PTPN11CD40CD40LG
SCHEMBL13994860	0.90	ENPP2 (0.45)	PHLPP2ENPP2PTPN11CD40CD40LG
SCHEMBL14374591	0.90	PHLPP2 (0.42)	PHLPP2ENPP2PTPN11SLC7A11CD40
SCHEMBL14374691	0.89	PHLPP2 (0.41)	PHLPP2ENPP2PTPN11SLC7A11CD40
SCHEMBL14374650	0.88	PHLPP2 (0.41)	PHLPP2ENPP2PTPN11SLC7A11CD40
SCHEMBL13239158	0.88	ENPP2 (0.43)	PHLPP2ENPP2PTPN11CD40CD40LG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-20070227388-A1	Tetrakisazo Compound, Coloring Matter for Recording, Ink Composition and Colored Article	NIPPON KAYAKU KABUSHIKI KAISHA (JP)	2007-10-04	—	—	US	disclosed