Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | GRN | P28799 | 1/20 | 0.37 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25455581 | 0.80 | MAPK1 (0.36) | MAPK1GRNSORT1 | |
| SCHEMBL14374861 | 0.77 | — | — | |
| SCHEMBL14374995 | 0.76 | MMP3 (0.32) | — | |
| SCHEMBL12670046 | 0.75 | GRN (0.33) | GRNSORT1 | |
| SCHEMBL14374825 | 0.75 | GRN (0.33) | GRNSORT1 | |
| SCHEMBL13632327 | 0.72 | MAPK1 (0.39) | MAPK1 | |
| SCHEMBL10077122 | 0.72 | EPHX1 (0.43) | GRNSORT1 | |
| SCHEMBL13676316 | 0.71 | MMP3 (0.36) | — | |
| SCHEMBL13637974 | 0.71 | MMP3 (0.36) | — | |
| SCHEMBL1709291 | 0.71 | MAPK1 (0.41) | MAPK1GRNSORT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7312211-B2 | Pryanone compounds useful as reversible inhibitors of cysteine proteases | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. | 2007-12-25 | — | — | US | disclosed |