Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | ABL1 | P00519 | 16/20 | 0.52 |
| ▸ | KIT | P10721 | 13/20 | 0.52 |
| ▸ | BCR | P11274 | 9/20 | 0.52 |
| ▸ | ABL2 | P42684 | 8/20 | 0.52 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.52 |
| ▸ | PLK4 | O00444 | 1/20 | 0.52 |
| ▸ | DDX3X | O00571 | 1/20 | 0.52 |
| ▸ | GAK | O14976 | 1/20 | 0.52 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.52 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.52 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.52 |
| ▸ | EGFR | P00533 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14375804 | 0.91 | ALDH1A1 (0.64) | ALDH1A1RAB9ANPC1ABL1KIT | |
| SCHEMBL14375837 | 0.85 | MAPK14 (0.49) | ALDH1A1RAB9ANPC1ABL1KIT | |
| SCHEMBL14375919 | 0.83 | ABL1 (0.54) | ABL1KITBCRABL2PDGFRA | |
| SCHEMBL14375798 | 0.80 | ABL1 (0.74) | ABL1KITBCRABL2PDGFRA | |
| SCHEMBL14375869 | 0.78 | ABL1 (0.72) | ABL1KITBCRABL2PDGFRA | |
| SCHEMBL14375838 | 0.78 | ABL1 (0.86) | ABL1KITBCRABL2PDGFRA | |
| SCHEMBL14375905 | 0.77 | ABL1 (0.41) | ABL1KITBCRABL2PDGFRA | |
| SCHEMBL14375799 | 0.77 | ABL1 (0.58) | ALDH1A1RAB9ANPC1ABL1KIT | |
| SCHEMBL14375894 | 0.76 | ABL1 (0.44) | ABL1KITBCRABL2PDGFRA | |
| SCHEMBL14375903 | 0.76 | PDGFRA (0.44) | ABL1KITBCRABL2PDGFRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7279576-B2 | Anti-cancer medicaments | DECIPHERA PHARMACEUTICALS, LLC (US) | 2007-10-09 | — | — | US | disclosed |
| US-7279576-B2 | Anti-cancer medicaments | DECIPHERA PHARMACEUTICALS, LLC (US) | 2007-10-09 | — | — | US | disclosed |