Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.53 |
| ▸ | MMP13 | P45452 | 3/20 | 0.53 |
| ▸ | PPARG | P37231 | 2/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.50 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.50 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.50 |
| ▸ | QPCT | Q16769 | 1/20 | 0.49 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HPGDS | O60760 | 1/20 | 0.49 |
| ▸ | PLK1 | P53350 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14376815 | 0.91 | HDAC6 (0.65) | HDAC6HDAC1MMP13HDAC2HDAC8 | |
| SCHEMBL27442099 | 0.81 | PPARG (0.53) | HDAC6HDAC1MMP13PPARGEPHX2 | |
| SCHEMBL13508672 | 0.80 | KCNH2 (0.62) | PPARGQPCTQPCTLALDH1A1SMN1; SMN2 | |
| SCHEMBL27441644 | 0.80 | QPCT (0.54) | MMP13QPCTQPCTLALDH1A1SMN1; SMN2 | |
| SCHEMBL22533916 | 0.80 | PPARG (0.52) | HDAC6HDAC1PPARGEPHX2 | |
| SCHEMBL22533972 | 0.80 | PPARG (0.52) | HDAC6HDAC1PPARGEPHX2 | |
| SCHEMBL6047768 | 0.79 | CYP11B1 (0.60) | QPCTQPCTLALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL22533807 | 0.79 | QPCT (0.53) | PPARGEPHX2QPCTQPCTLALDH1A1 | |
| SCHEMBL1180302 | 0.79 | EPHX2 (0.54) | PPARGEPHX2QPCTQPCTLALDH1A1 | |
| SCHEMBL27442450 | 0.79 | PPARG (0.52) | HDAC6HDAC1PPARGEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012178208-A2 | SELECTIVE INHIBITORS OF HISTONE DEACETYLASE ISOFORM 6 AND METHODS THEREOF | THE TRUSTEES OF THE STEVENS INSTITUTE OF TECHNOLOGY (US) | 2012-12-27 | — | — | WO | disclosed |