Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS | P04818 | 10/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | NQO2 | P16083 | 1/20 | 0.35 |
| ▸ | BRD1 | O95696 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7709575 | 0.83 | TYMS (0.49) | TYMSKDM4EMAPTPABPC1SMN1; SMN2 | |
| SCHEMBL9079081 | 0.81 | TYMS (0.50) | TYMSKDM4EMAPTPABPC1SMN1; SMN2 | |
| SCHEMBL6984126 | 0.79 | MAPT (0.62) | TYMSKDM4EMAPTPABPC1SMN1; SMN2 | |
| SCHEMBL9847741 | 0.77 | ALDH1A1 (0.59) | KDM4EMAPTPABPC1SMN1; SMN2MEN1 | |
| SCHEMBL9041820 | 0.76 | ALDH1A1 (0.63) | TYMSALOX15TDP1ALDH1A1HPGD | |
| SCHEMBL10267341 | 0.74 | TYMS (0.70) | TYMSKDM4EMAPTPABPC1SMN1; SMN2 | |
| SCHEMBL6719946 | 0.74 | TYMS (0.55) | TYMSALOX15TDP1MEN1POLB | |
| SCHEMBL8547705 | 0.74 | TYMS (0.46) | TYMSKDM4EMAPTPABPC1SMN1; SMN2 | |
| SCHEMBL9080061 | 0.73 | TYMS (0.46) | TYMSALDH1A1HPGDTSHRMAPK1 | |
| SCHEMBL2607526 | 0.73 | TYMS (0.41) | TYMSALOX15TDP1MEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7288567-B2 | Inhibitors of histone deacetylase | METHYLGENE INC. (CA) | 2007-10-30 | — | — | US | disclosed |