Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | IDH1 | O75874 | 1/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TOP2A | P11388 | 1/20 | 0.33 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26781740 | 0.84 | ALDH1A1 (0.53) | ALDH1A1CYP3A4IDH1S1PR4CA2 | |
| SCHEMBL13057612 | 0.82 | ALDH1A1 (0.52) | ALDH1A1CYP3A4IDH1S1PR4CA2 | |
| SCHEMBL5666942 | 0.81 | ALDH1A1 (0.64) | ALDH1A1CYP3A4IDH1CA2HSD17B10 | |
| SCHEMBL27672889 | 0.80 | CYP3A4 (0.51) | ALDH1A1CYP3A4IDH1S1PR4CA2 | |
| SCHEMBL13586898 | 0.80 | ALDH1A1 (0.53) | ALDH1A1CYP3A4IDH1S1PR4CA2 | |
| SCHEMBL25161986 | 0.78 | ALDH1A1 (0.47) | ALDH1A1CYP3A4IDH1S1PR4CA2 | |
| SCHEMBL5971176 | 0.78 | ALDH1A1 (0.55) | ALDH1A1CYP3A4IDH1HSD17B10LMNA | |
| SCHEMBL9686081 | 0.78 | ALDH1A1 (0.55) | ALDH1A1CYP3A4IDH1HSD17B10LMNA | |
| SCHEMBL13034135 | 0.77 | CYP3A4 (0.56) | ALDH1A1CYP3A4IDH1S1PR4CA2 | |
| SCHEMBL6589797 | 0.77 | MEN1 (0.52) | ALDH1A1CYP3A4CA2HSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1362053-B1 | TERMINALLY-BRANCHED POLYMERIC LINKERS AND POLYMERIC CONJUGATES CONTAINING THE SAME | ENZON INC (US) | 2007-11-14 | — | — | EP | disclosed |