Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 8/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 8/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 7/20 | 0.41 |
| ▸ | PRKACA | P17612 | 4/20 | 0.33 |
| ▸ | CDA | P32320 | 2/20 | 0.32 |
| ▸ | ENTPD1 | P49961 | 1/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.32 |
| ▸ | ENTPD2 | Q9Y5L3 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14384561 | 1.00 | ADORA3 (0.41) | ADORA3ADORA2AADORA1PRKACACDA | |
| SCHEMBL14387176 | 0.95 | ADORA3 (0.40) | ADORA3ADORA2AADORA1PRKACAROCK2 | |
| SCHEMBL13211027 | 0.95 | ADORA3 (0.40) | ADORA3ADORA2AADORA1PRKACAROCK2 | |
| SCHEMBL13211010 | 0.92 | FOLH1 (0.38) | ADORA3ADORA2AADORA1PRKACAROCK2 | |
| SCHEMBL13210939 | 0.91 | ADORA3 (0.40) | ADORA3ADORA2AADORA1PRKACAENTPD1 | |
| SCHEMBL13211025 | 0.91 | ADORA3 (0.37) | ADORA3ADORA2AADORA1CDAENTPD2 | |
| SCHEMBL13210961 | 0.86 | ADORA3 (0.39) | ADORA3ADORA2AADORA1PRKACAROCK2 | |
| SCHEMBL13211031 | 0.83 | ADORA3 (0.34) | ADORA3ADORA2AADORA1CDAEPHX2 | |
| SCHEMBL13210941 | 0.83 | FOLH1 (0.36) | ADORA3ADORA2AADORA1PRKACAROCK2 | |
| SCHEMBL13210959 | 0.81 | ADORA3 (0.36) | ADORA3ADORA2AADORA1CDAENTPD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1860113-A1 | Ectonucleotidase inhibitors | Rheinische Friedrich-Wilhelms-Universität Bonn (DE) | 2007-11-28 | — | — | EP | disclosed |