Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.72 |
| ▸ | MAPT | P10636 | 6/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.72 |
| ▸ | LMNA | P02545 | 2/20 | 0.66 |
| ▸ | MPI | P34949 | 1/20 | 0.66 |
| ▸ | THRB | P10828 | 3/20 | 0.60 |
| ▸ | THRA | P10827 | 2/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | EGFR | P00533 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9512833 | 0.88 | ALDH1A1 (0.84) | ALDH1A1MAPTKMT2ALMNAMPI | |
| SCHEMBL12919996 | 0.85 | TP53 (0.53) | ALDH1A1MAPTKMT2ALMNATP53 | |
| SCHEMBL7255774 | 0.84 | ALDH1A1 (1.00) | ALDH1A1MAPTKMT2ALMNAMPI | |
| SCHEMBL12123790 | 0.84 | ALDH1A1 (0.73) | ALDH1A1MAPTKMT2ALMNAMPI | |
| Hydrochloric Acid SCHEMBL7932182 | 0.82 | ALDH1A1 (0.74) | ALDH1A1MAPTKMT2ALMNAMPI | |
| SCHEMBL12123771 | 0.81 | ALDH1A1 (0.73) | ALDH1A1MAPTKMT2ALMNAMPI | |
| SCHEMBL12123826 | 0.81 | ALDH1A1 (0.73) | ALDH1A1MAPTKMT2ALMNAMPI | |
| SCHEMBL12123789 | 0.81 | ALDH1A1 (0.97) | ALDH1A1MAPTKMT2ALMNAMPI | |
| SCHEMBL321369 | 0.80 | ALDH1A1 (1.00) | ALDH1A1MAPTKMT2ALMNAMPI | |
| SCHEMBL15601796 | 0.80 | KMT2A (0.68) | ALDH1A1MAPTKMT2ALMNAMPI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007136790-A2 | INTRACELLULAR KINASE INHIBITORS | MANNKIND CORPORATION (US) | 2007-11-29 | — | — | WO | disclosed |