Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 18/20 | 0.59 |
| ▸ | HTR2C | P28335 | 13/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.46 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3946791 | 0.87 | HTR2A (0.63) | HTR2AHTR2C | |
| SCHEMBL3945364 | 0.84 | HTR2A (0.64) | HTR2AHTR2C | |
| SCHEMBL14384624 | 0.84 | HTR2A (0.59) | HTR2AHTR2C | |
| SCHEMBL3953706 | 0.82 | HTR2A (0.67) | HTR2AHTR2C | |
| SCHEMBL3953738 | 0.82 | HTR2A (0.64) | HTR2AHTR2C | |
| SCHEMBL3947369 | 0.82 | HTR2A (0.61) | HTR2AHTR2C | |
| SCHEMBL3954765 | 0.80 | HTR2A (0.68) | HTR2AHTR2C | |
| SCHEMBL3954051 | 0.79 | ALDH1A1 (0.63) | HTR2AHTR2C | |
| SCHEMBL29573278 | 0.77 | HTR2A (0.70) | HTR2AHTR2C | |
| SCHEMBL5061771 | 0.77 | HTR2A (0.70) | HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007136875-A2 | ACETAMIDE DERIVATIVES AS MODULATORS OF THE 5-HT2A SEROTONIN RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO | ARENA PHARMACEUTICALS, INC. (US) | 2007-11-29 | — | — | WO | disclosed |