Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 6/20 | 0.42 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.40 |
| ▸ | CKS1B | P61024 | 1/20 | 0.39 |
| ▸ | SKP1 | P63208 | 1/20 | 0.39 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.39 |
| ▸ | SUV39H2 | Q9H5I1 | 2/20 | 0.39 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5744791 | 1.00 | KCNH2 (0.42) | KCNH2SLC2A1MAP4K4CKS1BSKP1 | |
| SCHEMBL5744343 | 0.91 | KCNH2 (0.49) | KCNH2SLC2A1CKS1BSKP1SKP2 | |
| SCHEMBL3546417 | 0.90 | KCNH2 (0.50) | KCNH2SLC2A1MAP4K4CKS1BSKP1 | |
| SCHEMBL13315105 | 0.90 | KCNH2 (0.42) | KCNH2SLC2A1MAP4K4CKS1BSKP1 | |
| SCHEMBL2935789 | 0.87 | KCNH2 (0.43) | KCNH2SLC2A1MAP4K4CKS1BSKP1 | |
| SCHEMBL3551289 | 0.86 | SLC2A1 (0.51) | KCNH2SLC2A1MAP4K4 | |
| SCHEMBL3148938 | 0.83 | SLC2A1 (0.41) | KCNH2SLC2A1CKS1BSKP1SKP2 | |
| SCHEMBL3144945 | 0.83 | KCNA3 (0.40) | KCNH2SLC2A1MAP4K4CKS1BSKP1 | |
| SCHEMBL3209072 | 0.82 | MTNR1A (0.44) | SLC2A1MAP4K4CKS1BSKP1SKP2 | |
| SCHEMBL1075324 | 0.82 | KCNH2 (0.49) | KCNH2SLC2A1CKS1BSKP1SKP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007122258-A1 | TRYCLIC NITROGEN CONTAINING COMPOUNDS AND THEIR USE AS ANTIBACTERIALS | GLAXO GROUP LIMITED (GB) | 2007-11-01 | — | — | WO | disclosed |