Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 2/20 | 0.35 |
| ▸ | CCR5 | P51681 | 2/20 | 0.35 |
| ▸ | CCR8 | P51685 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.31 |
| ▸ | HTR2C | P28335 | 2/20 | 0.31 |
| ▸ | HTR2B | P41595 | 2/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6579639 | 0.76 | KDM4E (0.33) | CCR1CCR5CCR8KDM4ELMNA | |
| SCHEMBL31026580 | 0.76 | CCR1 (0.43) | CCR1CCR5CCR8KDM4ELMNA | |
| SCHEMBL10005371 | 0.76 | CCR1 (0.43) | CCR1CCR5CCR8KDM4ELMNA | |
| SCHEMBL10597341 | 0.73 | CCR1 (0.41) | CCR1CCR5CCR8KDM4ELMNA | |
| SCHEMBL31026576 | 0.73 | CCR1 (0.41) | CCR1CCR5CCR8KDM4ELMNA | |
| SCHEMBL31026589 | 0.73 | CCR1 (0.41) | CCR1CCR5CCR8KDM4ELMNA | |
| SCHEMBL9295436 | 0.73 | CCR1 (0.41) | CCR1CCR5CCR8KDM4ELMNA | |
| SCHEMBL31026569 | 0.73 | CCR1 (0.41) | CCR1CCR5CCR8KDM4ELMNA | |
| SCHEMBL1416036 | 0.73 | CCR1 (0.41) | CCR1CCR5CCR8KDM4ELMNA | |
| SCHEMBL30398550 | 0.73 | CCR1 (0.41) | CCR1CCR5CCR8KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007133349-A2 | FLUOROUS 2,2'-BIPYRIDINES AND FLUORINATED BIPHASIC SYSTEMS FOR LIGAND DESIGN | THE BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF NEVADA, LAS VEGAS (US) | 2007-11-22 | — | — | WO | disclosed |