SCHEMBL6579639

SCHEMBL6579639

FC(F)(F)C(F)(F)C(F)(F)CCc1ccnc2c1ccc1c(CCC(F)(F)C(F)(F)C(F)(F)F)ccnc12

nearest known ligand 0.33

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.33
CCR1 P32246 2/20 0.33
CCR5 P51681 2/20 0.33
CCR8 P51685 2/20 0.33
LMNA P02545 1/20 0.33
TP53 P04637 1/20 0.33
MAPT P10636 1/20 0.33
TSHR P16473 1/20 0.33
ALOX12 P18054 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14387293 0.76 CCR1 (0.35) KDM4ECCR1CCR5CCR8LMNA
SCHEMBL6577433 0.69 HTR1A (0.41) KDM4ECCR1
SCHEMBL5951485 0.68 LOXL2 (0.35) CCR1CCR5CCR8
SCHEMBL10005371 0.66 CCR1 (0.43) KDM4ECCR1CCR5CCR8LMNA
SCHEMBL31026580 0.66 CCR1 (0.43) KDM4ECCR1CCR5CCR8LMNA
SCHEMBL7565615 0.64 CCR1 (0.50) KDM4ECCR1CCR5CCR8LMNA
SCHEMBL30345465 0.64 KDM4E (0.68) KDM4ECCR1CCR5CCR8LMNA
SCHEMBL28976960 0.64 KDM4E (0.68) KDM4ECCR1CCR5CCR8LMNA
SCHEMBL30345468 0.64 KDM4E (0.68) KDM4ECCR1CCR5CCR8LMNA
SCHEMBL9295436 0.63 CCR1 (0.41) KDM4ECCR1CCR5CCR8LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1199556-B1 Optical sensor for measuring an analyte and method of manufacturing the same METTLER TOLEDO GMBH (CH) 2004-05-06 EP claimed
US-6653148-B2 Optical sensor for determining an analyte, and method of manufacturing the optical sensor METTLER-TOLEDO GMBH (CH) 2003-11-25 US claimed
US-20030017078-A1 Sensor matrix that is made up substantially of a fluoropolymer containing luminescent indicator with a metal complex of ruthenium, rhenium, rhodium or iridium, and with at least one at least partially fluorinated ligand. METTLER-TOLEDO GMBH (CH) 2003-01-23 US claimed
EP-1199556-A1 Optical sensor for measuring an analyte and method of manufacturing the same Mettler-Toledo GmbH (CH) 2002-04-24 EP claimed
EP-1199556-B1 Optical sensor for measuring an analyte and method of manufacturing the same METTLER TOLEDO GMBH (CH) 2004-05-06 EP disclosed
US-6653148-B2 Optical sensor for determining an analyte, and method of manufacturing the optical sensor METTLER-TOLEDO GMBH (CH) 2003-11-25 US disclosed
US-20030017078-A1 Sensor matrix that is made up substantially of a fluoropolymer containing luminescent indicator with a metal complex of ruthenium, rhenium, rhodium or iridium, and with at least one at least partially fluorinated ligand. METTLER-TOLEDO GMBH (CH) 2003-01-23 US disclosed
EP-1199556-A1 Optical sensor for measuring an analyte and method of manufacturing the same Mettler-Toledo GmbH (CH) 2002-04-24 EP disclosed