Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 5/20 | 0.63 |
| ▸ | MAOA | P21397 | 1/20 | 0.63 |
| ▸ | MAOB | P27338 | 1/20 | 0.63 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.63 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | GFER | P55789 | 1/20 | 0.51 |
| ▸ | KDM1A | O60341 | 4/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | ABL1 | P00519 | 1/20 | 0.50 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.50 |
| ▸ | BCR | P11274 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.43 |
| ▸ | CDK4 | P11802 | 1/20 | 0.43 |
| ▸ | CCND1 | P24385 | 1/20 | 0.43 |
| ▸ | JUN | P05412 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2775447 | 0.81 | CYP19A1 (0.68) | CYP19A1MAOAMAOBTRPA1NPC1 | |
| SCHEMBL2775445 | 0.81 | CYP19A1 (0.68) | CYP19A1MAOAMAOBTRPA1NPC1 | |
| SCHEMBL9419865 | 0.81 | TRPA1 (0.68) | MAOAMAOBTRPA1NPC1KDM1A | |
| SCHEMBL9419867 | 0.81 | TRPA1 (0.68) | MAOAMAOBTRPA1NPC1KDM1A | |
| Potassium SCHEMBL9419818 | 0.81 | TRPA1 (0.95) | TRPA1MAPTABL1ABCB1BCR | |
| SCHEMBL2774532 | 0.80 | CYP19A1 (0.86) | CYP19A1MAOAMAOBNPC1MAPT | |
| SCHEMBL27518377 | 0.80 | CYP19A1 (0.56) | CYP19A1MAOAMAOBTRPA1NPC1 | |
| SCHEMBL2774526 | 0.80 | CYP19A1 (0.86) | CYP19A1MAOAMAOBNPC1MAPT | |
| SCHEMBL29664559 | 0.80 | CYP19A1 (0.86) | CYP19A1MAOAMAOBNPC1MAPT | |
| SCHEMBL2775800 | 0.78 | CYP19A1 (1.00) | CYP19A1MAOAMAOBNPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7297820-B2 | Stilbene derivatives and their use for binding and imaging amyloid plaques | TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2007-11-20 | — | — | US | disclosed |
| US-7250525-B2 | Stilbene derivatives and their use for binding and imaging amyloid plaques | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2007-07-31 | — | — | US | disclosed |