Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 20/20 | 0.84 |
| ▸ | ITGAV | P06756 | 15/20 | 0.84 |
| ▸ | ITGA2B | P08514 | 11/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14387728 | 0.95 | ITGB3 (0.81) | ITGB3ITGAVITGA2B | |
| SCHEMBL14387729 | 0.92 | ITGB3 (0.84) | ITGB3ITGAVITGA2B | |
| SCHEMBL14356381 | 0.91 | ITGB3 (1.00) | ITGB3ITGAVITGA2B | |
| SCHEMBL13170290 | 0.91 | ITGB3 (1.00) | ITGB3ITGAVITGA2B | |
| SCHEMBL14387731 | 0.91 | ITGB3 (0.81) | ITGB3ITGAVITGA2B | |
| SCHEMBL14387907 | 0.91 | ITGB3 (0.86) | ITGB3ITGAVITGA2B | |
| SCHEMBL23718779 | 0.90 | ITGB3 (0.85) | ITGB3ITGAVITGA2B | |
| SCHEMBL14387730 | 0.90 | ITGB3 (0.85) | ITGB3ITGAVITGA2B | |
| SCHEMBL14356368 | 0.88 | ITGB3 (0.89) | ITGB3ITGAVITGA2B | |
| SCHEMBL14356372 | 0.88 | ITGB3 (0.85) | ITGB3ITGAVITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7300940-B2 | Integrin α-v β-3 antagonists for use in imaging and therapy | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2007-11-27 | — | — | US | disclosed |