Uridine Diphosphate Glucose

Uridine Diphosphate Glucose

SCHEMBL14389090

O=c1ccn(C2OC(COP(=O)(O)OP(=O)(O)O[C@H]3OC(CO)[C@H](O)[C@H](O)C3O)C(O)C2O)c(=O)[nH]1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ P2RY14 Q15391 13/20 1.00
▸ P2RY6 Q15077 8/20 1.00
▸ P2RY2 P41231 7/20 1.00
▸ P2RY4 P51582 6/20 0.98

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Uridine Diphosphate Glucose SCHEMBL1521087 1.00 P2RY14 (1.00) P2RY14P2RY6P2RY2P2RY4
Uridine Diphosphate Glucose SCHEMBL1521097 1.00 P2RY14 (1.00) P2RY14P2RY6P2RY2P2RY4
Uridine Diphosphate Glucose SCHEMBL1521147 1.00 P2RY14 (1.00) P2RY14P2RY6P2RY2P2RY4
Uridine Diphosphate Glucose SCHEMBL15589310 1.00 P2RY14 (1.00) P2RY14P2RY6P2RY2P2RY4
Uridine Diphosphate Glucose SCHEMBL14534383 1.00 P2RY14 (1.00) P2RY14P2RY6P2RY2P2RY4
Uridine Diphosphate Glucose SCHEMBL24747518 1.00 P2RY14 (1.00) P2RY14P2RY6P2RY2P2RY4
Uridine Diphosphate Glucose SCHEMBL9084902 1.00 P2RY14 (1.00) P2RY14P2RY6P2RY2P2RY4
Uridine Diphosphate Glucose SCHEMBL15314069 1.00 P2RY14 (1.00) P2RY14P2RY6P2RY2P2RY4
Uridine Diphosphate Glucose SCHEMBL20680471 1.00 P2RY14 (1.00) P2RY14P2RY6P2RY2P2RY4
Uridine Diphosphate Glucose SCHEMBL12016941 1.00 P2RY14 (1.00) P2RY14P2RY6P2RY2P2RY4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170007712-A1 GLYCOPEGYLATION METHODS AND PROTEINS/PEPTIDES PRODUCED BY THE METHODS NOVO NORDISK A/S (DK) 2017-01-12 — — US disclosed
US-20160200795-A1 FACTOR VIII: REMODELING AND GLYCOCONJUGATION OF FACTOR VIII NOVO NORDISK A/S (DK) 2016-07-14 — — US disclosed
US-20160193353-A1 FACTOR VIII: REMODELING AND GLYCOCONJUGATION OF FACTOR VIII NOVO NORDISK A/S (DK) 2016-07-07 — — US disclosed
US-20150343080-A1 GLYCOPEGYLATION METHODS AND PROTEINS/PEPTIDES PRODUCED BY THE METHODS NOVO NORDISK AS (DK) 2015-12-03 — — US disclosed
US-8853161-B2 Glycopegylation methods and proteins/peptides produced by the methods NOVO NORDISK A/S (DK) 2014-10-07 — — US disclosed
US-20140294762-A1 GLYCOPEGYLATION METHODS AND PROTEINS/PEPTIDES PRODUCED BY THE METHODS NOVO NORDISK A/S (DK) 2014-10-02 — — US disclosed
US-20140170728-A1 Factor IX: Remodeling and Glycoconjugation of Factor IX NOVO NORDISK A/S (DK) 2014-06-19 — — US disclosed
US-8076292-B2 Factor VIII: remodeling and glycoconjugation of factor VIII NOVO NORDISK A/S (DK) 2011-12-13 — — US disclosed
US-7297511-B2 Viricides; heptatis virus; complexing of interferon with glycan NEOSE TECHNOLOGIES, INC. (US) 2007-11-20 — — US disclosed
US-7265084-B2 Glycopegylation methods and proteins/peptides produced by the methods NEOSE TECHNOLOGIES, INC. (US) 2007-09-04 — — US disclosed
US-7265085-B2 Glycoconjugation methods and proteins/peptides produced by the methods NEOSE TECHNOLOGIES, INC. (US) 2007-09-04 — — US disclosed
US-7226903-B2 Interferon beta: remodeling and glycoconjugation of interferon beta NEOSE TECHNOLOGIES, INC. (US) 2007-06-05 — — US disclosed
US-20070042458-A1 ERYTHROPOIETIN: REMODELING AND GLYCOCONJUGATION OF ERYTHROPOIETIN NEOSE TECHNOLOGIES, INC. 2007-02-22 — — US disclosed
US-7179617-B2 Forming a convalent conjugate of a Factor IX peptide, removing X2 or a saccharyl subunit thereof from peptide forming a truncated glycan; contacting truncated glycan with glycosyltransferase and modified sugar donor under conditions suitable for glycosyltransferase to transfer a modified sugar moiety NEOSE TECHNOLOGIES, INC. (US) 2007-02-20 — — US disclosed
US-7173003-B2 Granulocyte colony stimulating factor: remodeling and glycoconjugation of G-CSF NEOSE TECHNOLOGIES, INC. (US) 2007-02-06 — — US disclosed
US-20070026485-A1 Glycopegylation methods and proteins/peptides produced by the methods NEOSE TECHNOLOGIES, INC. (US) 2007-02-01 — — US disclosed
US-20070027068-A1 Erythropoietin: remodeling and glycoconjugation of erythropoietin NOVO NORDISK A/S (DK) 2007-02-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160200795-A1 FACTOR VIII: REMODELING AND GLYCOCONJUGATION OF FACTOR VIII F13B, F8, F13A1 P2RY14 4236/4885P2RY6 3527/4885P2RY2 4558/4885
US-20070027068-A1 Erythropoietin: remodeling and glycoconjugation of erythropoietin EPOR, HBG2, HAMP P2RY14 4503/4885P2RY6 4343/4885P2RY2 4650/4885
US-20160193353-A1 FACTOR VIII: REMODELING AND GLYCOCONJUGATION OF FACTOR VIII F13B, F8, F13A1 P2RY14 4236/4885P2RY6 3527/4885P2RY2 4558/4885
US-20070026485-A1 Glycopegylation methods and proteins/peptides produced by the methods PTMS, ANPEP, NGLY1 P2RY14 4656/4885P2RY6 4626/4885P2RY2 4763/4885
US-20170007712-A1 GLYCOPEGYLATION METHODS AND PROTEINS/PEPTIDES PRODUCED BY THE METHODS PTMS, ANPEP, NGLY1 P2RY14 4656/4885P2RY6 4626/4885P2RY2 4763/4885
US-20070042458-A1 ERYTHROPOIETIN: REMODELING AND GLYCOCONJUGATION OF ERYTHROPOIETIN EPOR, HBG2, HAMP P2RY14 4503/4885P2RY6 4343/4885P2RY2 4650/4885
US-20150343080-A1 GLYCOPEGYLATION METHODS AND PROTEINS/PEPTIDES PRODUCED BY THE METHODS PTMS, ANPEP, NGLY1 P2RY14 4656/4885P2RY6 4626/4885P2RY2 4763/4885
US-20140294762-A1 GLYCOPEGYLATION METHODS AND PROTEINS/PEPTIDES PRODUCED BY THE METHODS PTMS, ANPEP, NGLY1 P2RY14 4656/4885P2RY6 4626/4885P2RY2 4763/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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