SCHEMBL14389949

SCHEMBL14389949

Cc1cn([C@H]2C[C@@H](OP(=O)(S)OC[C@H]3O[C@@H](n4cnc5c(=O)[nH]c(N)nc54)C[C@H]3OP(=O)(S)OC[C@H]3O[C@@H](n4ccc(N)nc4=O)C[C@H]3OP(=O)(S)OC[C@H]3O[C@@H](n4ccc(N)nc4=O)C[C@H]3O)[C@@H](CO)O2)c(=O)[nH]c1=O

nearest known ligand 0.67

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ F2 P00734 6/20 0.67
▸ P2RY2 P41231 3/20 0.53
▸ P2RY4 P51582 3/20 0.53
▸ P2RY6 Q15077 2/20 0.53
▸ POLB P06746 3/20 0.52
▸ TERT O14746 2/20 0.51
▸ DTYMK P23919 4/20 0.48
▸ TYMS P04818 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13326117 1.00 F2 (0.67) F2P2RY2P2RY4P2RY6POLB
SCHEMBL21504636 0.96 F2 (0.64) F2P2RY2P2RY4P2RY6POLB
SCHEMBL26189524 0.96 F2 (0.64) F2P2RY2P2RY4P2RY6POLB
SCHEMBL26189527 0.96 F2 (0.64) F2P2RY2P2RY4P2RY6POLB
SCHEMBL21489387 0.96 F2 (0.64) F2P2RY2P2RY4P2RY6POLB
SCHEMBL29552315 0.94 F2 (0.67) F2P2RY2P2RY4P2RY6POLB
SCHEMBL30055250 0.94 F2 (0.67) F2P2RY2P2RY4P2RY6POLB
SCHEMBL31103632 0.94 F2 (0.67) F2P2RY2P2RY4P2RY6POLB
SCHEMBL29551345 0.94 F2 (0.67) F2P2RY2P2RY4P2RY6POLB
SCHEMBL30478053 0.94 F2 (0.67) F2P2RY2P2RY4P2RY6POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070270359-A1 Nucleic Acid-Based Compounds and Methods of Use Thereof IYER RADHAKRISHNAN P 2007-11-22 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070270359-A1 Nucleic Acid-Based Compounds and Methods of Use Thereof NT5C3B, HAVCR2, NSUN2 F2 4405/4885P2RY2 1506/4885P2RY4 1039/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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