NT5C3B

7-methylguanosine phosphate-specific 5'-nucleotidase · Q969T7 · NT5C3B on Sugi Atlas →

8 patent compounds predicted against NT5C3B, 6 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL29438538 SCHEMBL29438538 0.64 1/20
SCHEMBL29466648 SCHEMBL29466648 0.62 1/20
SCHEMBL29824509 SCHEMBL29824509 0.61 1/20
SCHEMBL31122854 SCHEMBL31122854 0.61 1/20
SCHEMBL29390254 SCHEMBL29390254 0.60 1/20
SCHEMBL29352966 SCHEMBL29352966 0.46 1/20

Clinical trials — most relevant to NT5C3B by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Thiopurine EnhAnced Maintenance Therapy PHASE1/PHASE2COMPLETED
Therapeutic Safety and Efficacy of REP 2139 (REP 9AC') in HBV Infected Patients PHASE1/PHASE2COMPLETED
Temozolomide Monotherapy or in Combination With Olaparib in Patients With Triple Negative Breast Cancer (TNBC) PHASE2NOT_YET_RECRUITING
Safety and Efficacy of BMS-986504 in Unresectable Malignant Peripheral Nerve Sheath Tumor PHASE1/PHASE2NOT_YET_RECRUITING
Clinical Study of EBV-LMP1 Targeted DNAzyme to Treat Nasopharyngeal Carcinoma PHASE1/PHASE2COMPLETED
Treatment With Azacitidine of Recurrent Gliomas With IDH1/2 Mutation PHASE2UNKNOWN
5-aza-4'-Thio-2'-Deoxycytidine (Aza-TdC) in People With Advanced Solid Tumors PHASE1RECRUITING
Phase I Trial of 4'-Thio-2'-Deoxycytidine (TdCyd) in Patients With Advanced Solid Tumors PHASE1COMPLETED
A Phase 1 Safety and Dose Finding Study of GLIX1 in Adults With Recurrent or Progressive High-grade Glioma PHASE1RECRUITING
FTT PET/CT in Pancreatic Neuroendocrine Tumors PHASE1RECRUITING
Nucleoside Therapy in Patients With Telomere Biology Disorders PHASE1RECRUITING
DNA Adductomics for Colorectal Cancer Investigation nanUNKNOWN
Using the Epitranscriptome to Diagnose and Treat Gliomas nanRECRUITING
Epitranscriptomic Blood Biomarkers for Coronary Artery Disease - A Prospective Cohort Study (IHD-EPITRAN) nanUNKNOWN
Determination of the Effectiveness of Oral Chlorine Dioxide in the Treatment of COVID 19 nanUNKNOWN
Methylation of DNA in Children and Adolescents With Type 1 Diabetes Mellitus (METHYLDIAB) nanCOMPLETED
A Prospective Study of Molecular Detection of Salvageable Early Recurrent Nasopharyngeal Carcinoma After Radiotherapy nanCOMPLETED
Expression of TET1 Gene in Acute Leukaemia nanUNKNOWN
Epigenetics, DNA Methylation Patterns and Periodontal Disease nanCOMPLETED
Investigation of the Genetic and Environmental Causes of Autism: a Multi-Center Study nanNOT_YET_RECRUITING
Effect of DNMT SNPs on DNA Methylation in Primary ITP nanUNKNOWN
DNA Methylation and Autoimmune Thyroid Diseases nanCOMPLETED
Role of SF3B1 Mutation in Assessment of Acute and Chronic Lymphatic Leukemia nanNOT_YET_RECRUITING
The Value of circRNAs (hsa_circ_0004001) in Early Diagnosis of HCC nanUNKNOWN
DNA Methylation and Perioperative Pain Treatment nanCOMPLETED
Epigenetics, Vitamin C, and Abnormal Blood Cell Formation - Vitamin C in Patients With Low-Risk Myeloid Malignancies nanUNKNOWN
The Predictive Value of Guangzhou Panel for Recurrence in Early-stage Colorectal Cancer nanNOT_YET_RECRUITING
The Influence of Thiopurine Methyltransferase Activity on Toxicity After High-dose Methotrexate in Childhood Acute Lymphoblastic Leukemia nanCOMPLETED
Prognosis of METTL-14 in Endometrial Carcinoma nanNOT_YET_RECRUITING
Epigenetic and Neurochemical Correlates of Bipolar Disorder nanNOT_YET_RECRUITING

Related proteins — ESM-2 sequence neighbours (a NT5C3B binder may also engage these)

ProteinNameSimilarity
Q3UFY7 1.000 Q3UFY7 →
Q6AYP7 0.997 Q6AYP7 →
Q9H0P0 0.981 Q9H0P0 →
Q9D020 0.981 Q9D020 →
Q7SYN4 0.980 Q7SYN4 →
Q5ZKF6 0.975 Q5ZKF6 →
Q5ZID6 0.971 Q5ZID6 →
Q5PPH0 0.960 Q5PPH0 →
Q8K183 0.958 Q8K183 →
O35621 0.958 O35621 →
Q4R4U1 0.956 Q4R4U1 →
Q5R5F8 0.954 Q5R5F8 →
PMM2 Phosphomannomutase 2 0.954 landscape →
PDXK Pyridoxal kinase 0.954 landscape →
Q923S8 0.954 Q923S8 →
Q91YD4 0.954 Q91YD4 →
Q9NVE7 0.953 Q9NVE7 →
Q60HD6 0.953 Q60HD6 →
O35331 0.953 O35331 →
A0A0U1WZ18 0.952 A0A0U1WZ18 →
Q92871 0.951 Q92871 →
B1H369 0.951 B1H369 →
P82197 0.950 P82197 →
Q3SZJ9 0.950 Q3SZJ9 →
TRPM2 Transient receptor potential cation channel subfamily M member 2 0.949 landscape →
E9PTA2 0.949 E9PTA2 →
Q9QZ08 0.949 Q9QZ08 →
O46560 0.948 O46560 →
Q6DC64 0.948 Q6DC64 →
Q0II59 0.948 Q0II59 →