SCHEMBL14392

SCHEMBL14392

N=C1CCNC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18714609 0.81
SCHEMBL7620483 0.79
SCHEMBL267371 0.79
SCHEMBL8293877 0.77 ALDH1A1 (0.40)
SCHEMBL9116649 0.77 ALDH1A1 (0.40)
Hydrogen Sulfide SCHEMBL28150354 0.76
SCHEMBL21207769 0.69
SCHEMBL21283137 0.65
SCHEMBL21892287 0.65
SCHEMBL22908212 0.60

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4360866-A None JP disclosed
WO-2011047319-A2 ANTIMICROBIAL COMPOUNDS AND METHODS OF MAKING AND USING THE SAME RIB-X PHARMACEUTICALS, INC. (US) 2011-04-21 WO disclosed
WO-2010027236-A2 FUSED HETEROCYCLIC COMPOUND LG LIFE SCIENCES LTD. (KR) 2010-03-11 WO disclosed
JP-H04360866-A PRODUCTION OF 3-AMINOPYRROLIDINES SANKYO KAGAKU KK 1992-12-14 JP disclosed
CN-1032011-A Pyrrolo-imidazoles and imidazopyridine and application thereof SMITHKLINE BECKMAN CORP (US) 1989-03-29 CN disclosed