Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 5/20 | 0.43 |
| ▸ | THRA | P10827 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14392769 | 1.00 | ALDH1A1 (0.47) | ALDH1A1TP53GLAL3MBTL1THRB | |
| SCHEMBL27757303 | 1.00 | ALDH1A1 (0.47) | ALDH1A1TP53GLAL3MBTL1THRB | |
| SCHEMBL14368978 | 1.00 | ALDH1A1 (0.47) | ALDH1A1TP53GLAL3MBTL1THRB | |
| SCHEMBL14368970 | 1.00 | ALDH1A1 (0.47) | ALDH1A1TP53GLAL3MBTL1THRB | |
| SCHEMBL4429061 | 1.00 | ALDH1A1 (0.47) | ALDH1A1TP53GLAL3MBTL1THRB | |
| SCHEMBL14368980 | 1.00 | ALDH1A1 (0.47) | ALDH1A1TP53GLAL3MBTL1THRB | |
| SCHEMBL14368976 | 0.99 | ALDH1A1 (0.47) | ALDH1A1TP53GLAL3MBTL1THRB | |
| SCHEMBL4423115 | 0.91 | KDM4E (0.47) | ALDH1A1TP53THRBTHRAHRH3 | |
| SCHEMBL4423112 | 0.91 | KDM4E (0.47) | ALDH1A1TP53THRBTHRAHRH3 | |
| SCHEMBL14392597 | 0.91 | KDM4E (0.47) | ALDH1A1TP53THRBTHRAHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007126362-A1 | COMPOUNDS THAT ARE AGONISTS OF MUSCARINIC RECEPTORS AND THAT MAY BE EFFECTIVE IN TREATING PAIN, ALZHEIMER'S DISEASE AND/OR SCHIZOPHRENIA | ASTRAZENECA AB (SE) | 2007-11-08 | — | — | WO | disclosed |