Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 8/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1167213 | 0.88 | TYR (0.48) | TYRMEN1KMT2AMAPTMAPK1 | |
| SCHEMBL9892687 | 0.87 | TYR (0.40) | TYRMEN1KMT2AMAPTMAPK1 | |
| SCHEMBL693184 | 0.87 | TYR (0.47) | TYRMEN1KMT2AMAPTMAPK1 | |
| SCHEMBL10194576 | 0.87 | TYR (0.47) | TYRMEN1KMT2AMAPTMAPK1 | |
| SCHEMBL2633359 | 0.87 | TYR (0.47) | TYRMEN1KMT2AMAPTMAPK1 | |
| SCHEMBL2633308 | 0.87 | TYR (0.47) | TYRMEN1KMT2AMAPTMAPK1 | |
| SCHEMBL7921060 | 0.86 | TYR (0.51) | TYRMEN1KMT2AMAPTMAPK1 | |
| SCHEMBL14393043 | 0.85 | TYR (0.49) | TYRMEN1KMT2AMAPTMAPK1 | |
| SCHEMBL13763578 | 0.79 | TYR (0.43) | TYRMEN1KMT2AMAPTMAPK1 | |
| SCHEMBL8125938 | 0.79 | TYR (0.52) | TYRMEN1KMT2AMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1654261-B1 | HEPATITIS C INHIBITOR COMPOUNDS | BOEHRINGER INGELHEIM INT (DE) | 2007-11-14 | — | — | EP | disclosed |