Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 9/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MRE11 | P49959 | 1/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.38 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7926883 | 0.89 | ALDH1A1 (0.46) | TYRALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL10266220 | 0.88 | TYR (0.51) | TYRALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL14392811 | 0.86 | TYR (0.47) | TYRALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL14392961 | 0.80 | KMT2A (0.43) | TYRALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL10266218 | 0.80 | ALDH1A1 (0.48) | TYRALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL9890981 | 0.79 | TYR (0.54) | TYRMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL22110048 | 0.78 | ALDH1A1 (0.47) | TYRALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL3478854 | 0.78 | ALDH1A1 (0.47) | TYRALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL9892684 | 0.78 | ALDH1A1 (0.46) | TYRALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL11947493 | 0.78 | CTSB (0.46) | TYRALDH1A1KDM4EHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010033444-A1 | CRYSTALLINE FORMS OF A 2-THIAZOLYL- 4-QUINOLINYL-OXY DERIVATIVE, A POTENT HCV INHIBITOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-03-25 | — | — | WO | disclosed |