Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 15/20 | 0.51 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14395489 | 0.82 | ABL1 (0.43) | ABL1GSK3B | |
| SCHEMBL14097403 | 0.82 | ABL1 (0.60) | ABL1 | |
| SCHEMBL14395621 | 0.81 | ABL1 (0.44) | ABL1 | |
| SCHEMBL14395371 | 0.80 | NPC1 (0.43) | ABL1GSK3B | |
| SCHEMBL14395616 | 0.80 | ABL1 (0.43) | ABL1GSK3B | |
| SCHEMBL14395460 | 0.78 | ABL1 (0.46) | ABL1 | |
| SCHEMBL14097418 | 0.77 | ABL1 (0.49) | ABL1 | |
| SCHEMBL14395602 | 0.76 | ABL1 (0.38) | ABL1GSK3B | |
| SCHEMBL13788396 | 0.75 | ABL1 (0.39) | ABL1 | |
| SCHEMBL13788484 | 0.74 | ABL1 (0.38) | ABL1GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1341769-B1 | BACTERIAL GYRASE INHIBITORS AND USES THEREOF | VERTEX PHARMA (US) | 2007-10-17 | — | — | EP | disclosed |