Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 17/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13788469 | 0.81 | ABL1 (0.36) | ABL1GSK3B | |
| SCHEMBL13788480 | 0.74 | ABL1 (0.32) | ABL1 | |
| SCHEMBL14395370 | 0.74 | ABL1 (0.51) | ABL1GSK3B | |
| SCHEMBL13788396 | 0.73 | ABL1 (0.39) | ABL1 | |
| SCHEMBL13788383 | 0.72 | TUBB4A (0.37) | — | |
| SCHEMBL13823201 | 0.72 | ABL1 (0.36) | ABL1 | |
| SCHEMBL13788361 | 0.69 | ABL1 (0.35) | ABL1 | |
| SCHEMBL13788413 | 0.69 | ABL1 (0.35) | ABL1 | |
| SCHEMBL13823202 | 0.69 | ABL1 (0.39) | ABL1GSK3B | |
| SCHEMBL13788481 | 0.67 | KDM4E (0.36) | ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1592686-B1 | GYRASE INHIBITORS AND USES THEREOF | VERTEX PHARMA (US) | 2009-07-08 | — | — | EP | disclosed |