SCHEMBL1439552

SCHEMBL1439552

O=COCOCC1CC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1439473 0.91 ADH1B (0.34)
SCHEMBL4773943 0.89 ADH1B (0.38)
SCHEMBL30435158 0.79 SLC1A3 (0.34)
SCHEMBL133081 0.79
SCHEMBL4771678 0.77
SCHEMBL6180210 0.76
SCHEMBL11529416 0.76 TSHR (0.32)
SCHEMBL29163603 0.71 SLC1A3 (0.31)
SCHEMBL10749687 0.70
SCHEMBL457302 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008065408-A9 MODULATION OF PROSTAGLANDIN/CYCLOOXYGENASE METABOLIC PATHWAYS HUNTER-FLEMING LIMITED (GB) 2011-03-03 WO disclosed
US-20090259043-A1 TRICYCLIC CYTOPROTECTIVE COMPOUNDS HUNTER-FLEMING LIMITED (GB) 2009-10-15 US disclosed
EP-2097079-A2 MODULATION OF PROSTAGLANDIN/CYCLOOXYGENASE METABOLIC PATHWAYS Hunter-Fleming Limited (GB) 2009-09-09 EP disclosed
WO-2008065408-A2 MODULATION OF PROSTAGLANDIN/CYCLOOXYGENASE METABOLIC PATHWAYS HUNTER-FLEMING LIMITED (GB) 2008-06-05 WO disclosed
EP-1848426-A2 TRICYCLIC CYTOPROTECTIVE COMPOUNDS Hunter-Fleming Limited (GB) 2007-10-31 EP disclosed
WO-2006082409-A2 TRICYCLIC CYTOPROTECTIVE COMPOUNDS HUNTER-FLEMING LIMITED (GB) 2006-08-10 WO disclosed
EP-1471901-A1 SPERMIDINE DERIVATIVES FOR THE TREATMENT OF CHRONIC NEURODEGENERATIVE DISEASES UNIVERSITY OF SOUTHAMPTON (GB) 2004-11-03 EP disclosed
WO-2003066037-A1 SPERMIDINE DERIVATIVES FOR THE TREATMENT OF CHRONIC NEURODEGENERATIVE DISEASES UNIVERSITY OF SOUTHAMPTON (GB) 2003-08-14 WO disclosed
EP-1040096-A1 NEUROPROTECTIVE AGENTS THE UNIVERSITY OF SOUTHAMPTON (GB) 2000-10-04 EP disclosed
WO-1999031049-A1 NEUROPROTECTIVE AGENTS UNIVERSITY OF SOUTHAMPTON (GB) 1999-06-24 WO disclosed
EP-0804416-A1 HETEROCYCLIC COMPOUNDS, USEFUL AS ALLOSTERIC EFFECTORS AT MUSCARINIC RECEPTORS SANKYO COMPANY LIMITED (JP) 1997-11-05 EP disclosed
WO-1996003377-A1 HETEROCYCLIC COMPOUNDS, USEFUL AS ALLOSTERIC EFFECTORS AT MUSCARINIC RECEPTORS SANKYO COMPANY, LIMITED (JP) 1996-02-08 WO disclosed