Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 6/20 | 0.46 |
| ▸ | PIK3CD | O00329 | 5/20 | 0.46 |
| ▸ | PIK3CB | P42338 | 5/20 | 0.46 |
| ▸ | PI4KA | P42356 | 5/20 | 0.46 |
| ▸ | PIK3CG | P48736 | 5/20 | 0.46 |
| ▸ | PI4KB | Q9UBF8 | 5/20 | 0.46 |
| ▸ | PIP5K1C | O60331 | 1/20 | 0.46 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.45 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.43 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.43 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | LIPC | P11150 | 4/20 | 0.41 |
| ▸ | LIPG | Q9Y5X9 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14397009 | 0.86 | PIK3CD (0.64) | PIK3CAPIK3CDPIK3CBPI4KAPIK3CG | |
| SCHEMBL14396839 | 0.86 | PIK3CD (0.51) | PIK3CAPIK3CDPIK3CBPI4KAPIK3CG | |
| SCHEMBL14396769 | 0.84 | PIK3CA (0.52) | PIK3CAPIK3CDPIK3CBPI4KAPIK3CG | |
| SCHEMBL14396768 | 0.84 | PIK3CD (0.63) | PIK3CAPIK3CDPIK3CBPI4KAPIK3CG | |
| SCHEMBL14396651 | 0.83 | CSF1R (0.47) | PIK3CAMKNK1CSF1RCYP3A4 | |
| SCHEMBL14397011 | 0.82 | PIK3CD (0.52) | PIK3CAPIK3CDPIK3CBPI4KAPIK3CG | |
| SCHEMBL14396831 | 0.82 | PIK3CD (0.61) | PIK3CAPIK3CDPIK3CBPI4KAPIK3CG | |
| SCHEMBL14396776 | 0.82 | PIK3CD (0.52) | PIK3CAPIK3CDPIK3CBPI4KAPIK3CG | |
| SCHEMBL14396840 | 0.81 | PIK3CD (0.47) | PIK3CAPIK3CDPIK3CBPI4KAPIK3CG | |
| SCHEMBL2677788 | 0.81 | CSF1R (0.53) | PIK3CAMKNK1CSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007121484-A2 | 6-O-SUBSTITUTED BENZOXAZOLE AND BENZOTHIAZOLE COMPOUNDS AND METHODS OF INHIBITING CSF-1R SIGNALING | NOVARTIS AG (CH) | 2007-10-25 | — | — | WO | disclosed |