SCHEMBL14397103

SCHEMBL14397103

Cc1ccc(Oc2ccc(C)c(C(F)(F)F)c2)cc1Br

nearest known ligand 0.45

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
AR P10275 14/20 0.45
RHEB Q15382 1/20 0.41
KDR P35968 1/20 0.37
CDK8 P49336 1/20 0.36
S1PR1 P21453 2/20 0.35
MGLL Q99685 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14649764 0.87 AR (0.41) ARKDR
SCHEMBL14618669 0.82 AR (0.64) ARRHEBKDRCDK8
SCHEMBL8736872 0.81 AR (0.50) ARRHEBS1PR1MGLL
SCHEMBL21346441 0.81 AR (0.50) ARRHEBKDRCDK8
SCHEMBL2900162 0.80 EPHX2 (0.44) ARRHEB
SCHEMBL8737846 0.79 AR (0.60) ARRHEBKDRCDK8
SCHEMBL14407088 0.79 AR (0.46) ARRHEBKDRCDK8
SCHEMBL14407096 0.78 AR (0.67) AR
SCHEMBL14397642 0.78 RAB9A (0.37) AR
SCHEMBL14397648 0.77 AR (0.44) AR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007113327-A2 FUNGICIDE N-CYCLOPROPYL-SULFONYLAMIDE DERIVATIVES BAYER CROPSCIENCE SA (FR) 2007-10-11 WO disclosed