Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | TGM2 | P21980 | 1/20 | 0.37 |
| ▸ | TGM1 | P22735 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.30 |
| ▸ | PLAU | P00749 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22492987 | 0.69 | NOS1 (0.69) | NOS1ALDH1A1TGM2TGM1MEN1 | |
| SCHEMBL23130448 | 0.66 | NOS1 (0.41) | NOS1ALDH1A1TGM2TGM1MEN1 | |
| SCHEMBL18600016 | 0.66 | NOS1 (0.44) | NOS1ALDH1A1TGM2TGM1MEN1 | |
| Hydrochloric Acid SCHEMBL11559050 | 0.65 | NOS1 (0.53) | NOS1ALDH1A1TGM2TGM1MEN1 | |
| Hydrochloric Acid SCHEMBL3432525 | 0.64 | NOS1 (0.96) | NOS1ALDH1A1TGM2TGM1MEN1 | |
| SCHEMBL15382058 | 0.63 | NOS1 (0.50) | NOS1ALDH1A1TGM2TGM1MEN1 | |
| SCHEMBL12230854 | 0.63 | NOS1 (0.50) | NOS1ALDH1A1TGM2TGM1MEN1 | |
| SCHEMBL24271351 | 0.63 | NOS1 (0.50) | NOS1ALDH1A1TGM2TGM1MEN1 | |
| SCHEMBL15233142 | 0.63 | NOS1 (0.50) | NOS1ALDH1A1TGM2TGM1MEN1 | |
| SCHEMBL23024744 | 0.61 | NOS1 (0.48) | NOS1ALDH1A1TGM2TGM1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007118318-A1 | USE OF IMIDAZO[2,1-b)]-1,3,4-THIADIAZOLE-2-SULFONAMIDE COMPOUNDS TO TREAT NEUROPATHIC PAIN | AEGERA THERAPEUTICS INC. (CA) | 2007-10-25 | — | — | WO | disclosed |