Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 2/20 | 0.45 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | PREP | P48147 | 7/20 | 0.41 |
| ▸ | FNTA | P49354 | 1/20 | 0.39 |
| ▸ | FNTB | P49356 | 1/20 | 0.39 |
| ▸ | GYS1 | P13807 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.37 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10516032 | 0.85 | ACE (0.47) | ACEPREPL3MBTL1ITGB1ITGA4 | |
| SCHEMBL10340335 | 0.77 | ACE (0.44) | ACEPREPGYS1L3MBTL1 | |
| SCHEMBL3750871 | 0.77 | ACE (0.44) | ACEPREPGYS1L3MBTL1 | |
| SCHEMBL10516360 | 0.77 | ACE (0.50) | ACEPREP | |
| SCHEMBL10516349 | 0.77 | ACE (0.50) | ACEPREP | |
| SCHEMBL3144779 | 0.76 | PREP (0.66) | ACEPREP | |
| SCHEMBL10370731 | 0.76 | PREP (0.66) | ACEPREP | |
| SCHEMBL14407879 | 0.75 | ALDH1A1 (0.54) | ACEITGB1ITGA4 | |
| SCHEMBL5833620 | 0.75 | ALDH1A1 (0.54) | ACEITGB1ITGA4 | |
| SCHEMBL10516925 | 0.75 | NPC1 (0.49) | ACEPREP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007117180-A1 | AZAHETEROCYCLES, COMBINATORY LIBRARY, FOCUSED LIBRARY, PHARMACEUTICAL COMPOSITION AND METHODS FOR THE PRODUCTION THEREOF | 'CHEMICAL DIVERSITY RESEARCH INSTITUTE' LTD. (RU) | 2007-10-18 | — | — | WO | disclosed |