Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 12/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.34 |
| ▸ | PSD | A5PKW4 | 1/20 | 0.34 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4175233 | 0.77 | GRM1 (0.59) | GRM1 | |
| SCHEMBL4701116 | 0.77 | GRM1 (0.40) | PTGS2PTGS1GRM1HSD11B1 | |
| SCHEMBL4163385 | 0.66 | GRM1 (0.60) | GRM1 | |
| SCHEMBL4164739 | 0.66 | GRM1 (0.44) | PTGS2PTGS1GRM1BRD4RIPK2 | |
| SCHEMBL4168810 | 0.66 | GRM1 (0.41) | PTGS2PSDGRM1MCHR1RIPK2 | |
| SCHEMBL4699767 | 0.66 | GRM1 (0.41) | PTGS2PTGS1GRM1RIPK2 | |
| SCHEMBL4164801 | 0.66 | GRM1 (0.59) | GRM1 | |
| SCHEMBL4701666 | 0.65 | GRM1 (0.41) | PTGS2PTGS1GRM1RIPK2 | |
| SCHEMBL4167589 | 0.65 | GRM1 (0.61) | GRM1 | |
| SCHEMBL4165708 | 0.65 | GRM1 (0.42) | PTGS2GRM1MCHR1RIPK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007120454-A1 | AZOLOPYRIMIDINES AS INHIBITORS OF CANNABINOID 1 ACTIVITY | IRM LLC (BM) | 2007-10-25 | — | — | WO | disclosed |