Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F12 | P00748 | 2/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.47 |
| ▸ | MGAM | O43451 | 6/20 | 0.46 |
| ▸ | AMY1A | P0DUB6 | 6/20 | 0.46 |
| ▸ | GAA | P10253 | 6/20 | 0.46 |
| ▸ | SI | P14410 | 6/20 | 0.46 |
| ▸ | MGAM2 | Q2M2H8 | 6/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | ATM | Q13315 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12321787 | 0.86 | KMT2A (0.56) | F12CA12CA1CA2CA9 | |
| SCHEMBL13911403 | 0.84 | KMT2A (0.50) | F12CA12CA1CA2CA9 | |
| SCHEMBL3936368 | 0.84 | CA12 (0.54) | F12CA12CA1CA2CA9 | |
| SCHEMBL12204565 | 0.83 | SMN1; SMN2 (0.62) | CA12CA1CA2CA9SMN1; SMN2 | |
| SCHEMBL26209909 | 0.81 | CA12 (0.46) | F12CA12CA1CA2CA9 | |
| SCHEMBL503004 | 0.78 | KCNMA1 (0.59) | CA12CA1CA2CA9SMN1; SMN2 | |
| SCHEMBL3977744 | 0.78 | TDP1 (0.56) | F12SMN1; SMN2KCNMA1MGAMAMY1A | |
| SCHEMBL25008763 | 0.78 | SMN1; SMN2 (0.48) | F12CA12CA1CA2CA9 | |
| SCHEMBL15632082 | 0.78 | SMN1; SMN2 (0.57) | CA12CA1CA2CA9SMN1; SMN2 | |
| SCHEMBL31227376 | 0.78 | PCSK9 (0.51) | KMT2APCSK9POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007120454-A1 | AZOLOPYRIMIDINES AS INHIBITORS OF CANNABINOID 1 ACTIVITY | IRM LLC (BM) | 2007-10-25 | — | — | WO | disclosed |