Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHF8 | Q9UPP1 | 5/20 | 0.52 |
| ▸ | KDM2A | Q9Y2K7 | 5/20 | 0.52 |
| ▸ | EGLN1 | Q9GZT9 | 4/20 | 0.45 |
| ▸ | KDM6B | O15054 | 2/20 | 0.45 |
| ▸ | KDM5C | P41229 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.41 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.41 |
| ▸ | KDM4A | O75164 | 4/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 4/20 | 0.40 |
| ▸ | KDM7A | Q6ZMT4 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3026178 | 0.82 | ALDH1A1 (0.38) | PHF8KDM2AEGLN1KDM6BKDM5C | |
| SCHEMBL14397786 | 0.82 | PHF8 (0.37) | PHF8KDM2AEGLN1KDM6BKDM5C | |
| SCHEMBL4508931 | 0.78 | PHF8 (0.58) | PHF8KDM2AEGLN1KDM6BKDM5C | |
| SCHEMBL15987580 | 0.78 | CA12 (0.42) | PHF8KDM2AEGLN1KDM6BKDM5C | |
| SCHEMBL17119845 | 0.76 | PHF8 (0.56) | PHF8KDM2AEGLN1KDM6BKDM5C | |
| SCHEMBL2273019 | 0.75 | — | — | |
| SCHEMBL25132420 | 0.74 | — | — | |
| SCHEMBL10441550 | 0.74 | — | — | |
| SCHEMBL13941296 | 0.74 | — | — | |
| SCHEMBL867897 | 0.74 | KMT2A (0.68) | NPC1RAB9AKDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007117180-A1 | AZAHETEROCYCLES, COMBINATORY LIBRARY, FOCUSED LIBRARY, PHARMACEUTICAL COMPOSITION AND METHODS FOR THE PRODUCTION THEREOF | 'CHEMICAL DIVERSITY RESEARCH INSTITUTE' LTD. (RU) | 2007-10-18 | — | — | WO | disclosed |