Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | MIF | P14174 | 2/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13989159 | 0.81 | KMT2A (0.53) | KMT2AMEN1ATMPTGS2MAPT | |
| SCHEMBL13989158 | 0.80 | KMT2A (0.49) | KMT2AMEN1PTGS2MAPTALDH1A1 | |
| SCHEMBL16070432 | 0.79 | CHKA (0.43) | RAB9ANPC1KMT2AMAPTNLRP3 | |
| SCHEMBL16070435 | 0.78 | PTGS1 (0.40) | RAB9ANPC1KMT2AMEN1ATM | |
| SCHEMBL12432783 | 0.76 | MAPT (0.65) | RAB9ANPC1KMT2AMEN1ATM | |
| SCHEMBL15624281 | 0.75 | RAB9A (0.38) | RAB9ANPC1KMT2AMEN1MAPT | |
| SCHEMBL14077330 | 0.74 | KMT2A (0.44) | KMT2AMEN1PTGS1PTGS2MAPT | |
| Iodomethane SCHEMBL710788 | 0.72 | MAPT (0.60) | RAB9ANPC1KMT2AMEN1ATM | |
| Iodomethane SCHEMBL4424533 | 0.72 | MAPT (0.60) | RAB9ANPC1KMT2AMEN1ATM | |
| SCHEMBL15882807 | 0.72 | KMT2A (0.45) | KMT2AMEN1ATMPTGS2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2677996-B1 | COMPOSITION FOR DYEING KERATINOUS FIBRES COMPRISING A DIRECT DYE HAVING A DISULPHIDE/THIOL FUNCTIONAL GROUP, A THICKENING POLYMER, AN ETHOXYLATED FATTY ALCOHOL AND/OR A NONIONIC SURFACTANT, AN ALKALINE AGENT AND A REDUCING AGENT | L'ORÉAL (FR) | 2017-11-29 | — | — | EP | disclosed |
| EP-2018847-B1 | Hair composition comprising at least one direct disulfide dye and at least one alkali hydroxide agent and method of simultaneous styling and dyeing. | ORÉAL L (FR) | 2014-09-17 | — | — | EP | disclosed |
| WO-2007110542-A2 | METHOD OF DYEING AND LIGHTENING KERATIN MATERIALS IN THE PRESENCE OF A REDUCING AGENT COMPRISING A FLUORESCENT DISULPHIDE DYE | L'OREAL (FR) | 2007-10-04 | — | — | WO | disclosed |