Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | CA12 | O43570 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA7 | P43166 | 2/20 | 0.48 |
| ▸ | CA9 | Q16790 | 2/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.48 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CTSD | P07339 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.45 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CBX7 | O95931 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18415530 | 0.83 | CA12 (0.52) | ALDH1A1CA12CA1CA2CA7 | |
| SCHEMBL7500143 | 0.82 | KDM4E (0.53) | ALDH1A1CA12CA1CA2CA7 | |
| SCHEMBL2095565 | 0.82 | CA12 (0.50) | ALDH1A1CA12CA1CA2CA7 | |
| SCHEMBL2095568 | 0.82 | CA12 (0.55) | ALDH1A1CA12CA1CA2CA7 | |
| SCHEMBL7500132 | 0.80 | CA12 (0.48) | ALDH1A1CA12CA1CA2CA7 | |
| SCHEMBL2755842 | 0.80 | ALDH1A1 (0.77) | ALDH1A1MAPTGAAHTTHSD17B10 | |
| SCHEMBL9021594 | 0.80 | CA12 (0.46) | ALDH1A1CA12CA1CA2CA7 | |
| SCHEMBL10816887 | 0.79 | ALDH1A1 (0.45) | ALDH1A1CA12CA1CA2CA7 | |
| SCHEMBL5273139 | 0.79 | NR3C2 (0.45) | ALDH1A1NR3C2MAPTHTTHSD17B10 | |
| SCHEMBL18415504 | 0.78 | CA12 (0.47) | ALDH1A1CA12CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112300172-B | Bruton tyrosine kinase inhibitors | 比奥根MA公司 | 2024-01-16 | — | — | CN | disclosed |
| WO-2011029046-A1 | BRUTON'S TYROSINE KINASE INHIBITORS | BIOGEN IDEC MA INC. (US) | 2011-03-10 | — | — | WO | disclosed |