Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 5/20 | 0.50 |
| ▸ | CA1 | P00915 | 3/20 | 0.50 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LDHA | P00338 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL11823002 | 0.86 | CA4 (0.50) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL25 | 0.86 | — | — | |
| Bicarbonate SCHEMBL551759 | 0.86 | CA4 (0.50) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL632939 | 0.86 | CA4 (0.50) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL21951320 | 0.86 | CA4 (0.50) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL888439 | 0.86 | — | — | |
| Bicarbonate SCHEMBL24341 | 0.86 | — | — | |
| Bicarbonate SCHEMBL20604683 | 0.86 | CA4 (0.50) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL21951326 | 0.86 | — | — | |
| Bicarbonate SCHEMBL504408 | 0.86 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 366 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117701044-B | Multiphase dysprosium doped zirconia sealing coating, preparation method thereof and device with high abrasion performance | 北矿新材科技有限公司 | 2024-09-03 | — | — | CN | claimed |
| CN-111952032-B | Preparation method of sintered NdFeB permanent magnet with low boron, low heavy rare earth and high coercivity | 赣州嘉通新材料有限公司 | 2024-07-23 | — | — | CN | claimed |
| CN-118256746-A | Separation method of terbium element and adjacent lanthanide rare earth element | 中国科学院赣江创新研究院 | 2024-06-28 | — | — | CN | claimed |
| CN-118006330-A | Dysprosium-calcium-indium-gallium-zirconium garnet Dan Jilan light-yellow light long afterglow fluorescent powder and preparation method and application thereof | 广州医科大学附属口腔医院（广州医科大学羊城医院） | 2024-05-10 | — | — | CN | claimed |
| CN-117701044-A | Multiphase dysprosium doped zirconia sealing coating, preparation method thereof and device with high abrasion performance | 北矿新材科技有限公司 | 2024-03-15 | — | — | CN | claimed |
| CN-111604086-B | Preparation method and application of platinum-based normal paraffin aromatization catalyst | 山东省科学院能源研究所 | 2024-01-19 | — | — | CN | claimed |
| CN-117185336-B | Controllable preparation method for superfine dysprosium oxide specific surface area | 中稀(江苏)稀土有限公司 | 2024-01-16 | — | — | CN | claimed |
| US-11865509-B2 | Porous molding | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2024-01-09 | — | — | US | claimed |
| CN-117185336-A | Controllable preparation method for superfine dysprosium oxide specific surface area | 中稀(江苏)稀土有限公司 | 2023-12-08 | — | — | CN | claimed |
| CN-117105257-A | Method for preparing rare earth fluoride by carbon circulation | 包头市玺骏稀土有限责任公司 | 2023-11-24 | — | — | CN | claimed |
| CN-101012500-A | Method for fully separating high-purity rare earth oxide from low-yttrium medium-heavy rare earth ore | CHANGZHOU HUANAN CHEMICAL INDU (CN) | 2007-08-08 | — | — | CN | claimed |
| CN-101012501-A | Method for fully separating high-purity rare earth oxide from yttrium-rich rare earth ore | JINTAN XINAN CHEMICAL INDUSTRY (CN) | 2007-08-08 | — | — | CN | claimed |
| CN-101012506-A | Method for preparing ultra-thin highly-pure dysprosium oxide by beneficiated terbium-dysprosium | CHANGZHOU HUANAN CHEMICAL INDU (CN) | 2007-08-08 | — | — | CN | claimed |
| WO-2005054132-A1 | TAGGED POLYMERIC MATERIALS AND METHODS FOR THEIR PREPARATION | ORICA AUSTRALIA PTY LTD (AU) | 2005-06-16 | — | — | WO | claimed |
| EP-1284941-B1 | CERAMIC MATERIAL, METHOD FOR PRODUCTION AND USE THEREOF AND COMPONENT THEREWITH | EPCOS AG (DE) | 2004-03-24 | — | — | EP | claimed |
| EP-1284941-A1 | CERAMIC MATERIAL, METHOD FOR PRODUCTION AND USE THEREOF AND COMPONENT THEREWITH | EPCOS AG (DE) | 2003-02-26 | — | — | EP | claimed |
| WO-2001090027-A1 | CERAMIC MATERIAL, METHOD FOR PRODUCTION AND USE THEREOF AND COMPONENT THEREWITH | EPCOS AG (DE) | 2001-11-29 | — | — | WO | claimed |
| CN-1032833-C | Neutron and gamma ray radiation shielding material | TIANJIN TEXTILE ENGINEERING IN (CN) | 1996-09-18 | — | — | CN | claimed |
| CN-1089055-A | Neutron and gamma-ray radiation shielding material | TIANJIN TEXTILE ENGRG COLLEGE (CN) | 1994-07-06 | — | — | CN | claimed |
| US-4211882-A | OXIDIZING P-TOLUALDEHYDE, CATALYST CONSISTING OF A MANGANESE COMPOUND, A COBALT COMPOUND, A BROMINE COMPOUND, AND A NICKEL, IRON, CHROMIUM, OR LANTHANIDE COMPOUND | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1980-07-08 | — | — | US | claimed |