Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 5/20 | 0.50 |
| ▸ | CA1 | P00915 | 3/20 | 0.50 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LDHA | P00338 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL31457920 | 0.94 | — | — | |
| Bicarbonate SCHEMBL5586503 | 0.94 | CA4 (0.60) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL29733395 | 0.94 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL29857380 | 0.94 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL11775943 | 0.86 | CA4 (0.50) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL5485082 | 0.86 | CA4 (0.50) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL60565 | 0.86 | — | — | |
| Bicarbonate SCHEMBL21951320 | 0.86 | CA4 (0.50) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL21951326 | 0.86 | — | — | |
| Bicarbonate SCHEMBL11823002 | 0.86 | CA4 (0.50) | CA4CA1FAHD1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 120 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117344382-A | Compound alkali metal borophosphate and alkali metal borophosphate nonlinear optical crystal, and preparation method and application thereof | 天津理工大学 | 2024-01-05 | — | — | CN | claimed |
| US-20230416093-A1 | Compounds Alkali Metal Borophosphates, Alkali Metal Borophosphates Nonlinear Optical Crystals as well as Preparation Method and Application thereof | TIANJIN UNIVERSITY OF TECHNOLOGY (CN) | 2023-12-28 | — | — | US | claimed |
| CN-113668056-B | Compound molybdenum zinc potassium phosphate and molybdenum zinc potassium phosphate nonlinear optical crystal, preparation method and application | 天津理工大学 | 2023-11-24 | — | — | CN | claimed |
| CN-115353623-B | Polyimide photosensitive material and preparation method and application thereof | 中山大学 | 2023-10-13 | — | — | CN | claimed |
| CN-115353623-A | Polyimide photosensitive material and preparation method and application thereof | 中山大学 | 2022-11-18 | — | — | CN | claimed |
| CN-113846379-A | Compound bismuth cadmium phosphate and bismuth cadmium phosphate scintillation crystal, and preparation method and application thereof | 天津理工大学 | 2021-12-28 | — | — | CN | claimed |
| CN-113668056-A | Compound molybdenum zinc potassium phosphate and molybdenum zinc potassium phosphate nonlinear optical crystal, and preparation method and application thereof | 天津理工大学 | 2021-11-19 | — | — | CN | claimed |
| CN-113668055-A | Compound potassium molybdenum phosphate and potassium molybdenum phosphate nonlinear optical crystal, and preparation method and application thereof | 天津理工大学 | 2021-11-19 | — | — | CN | claimed |
| US-7601881-B2 | Isomerization catalyst and process | UOP LLC (US) | 2009-10-13 | — | — | US | claimed |
| US-7538064-B2 | Isomerization catalyst and process | UOP LLC (US) | 2009-05-26 | — | — | US | claimed |
| US-20080280755-A1 | Isomerization Catalyst and Process | GILLESPIE RALPH D | 2008-11-13 | — | — | US | claimed |
| US-20080128327-A1 | Isomerization Catalyst and Process | GILLESPIE RALPH D | 2008-06-05 | — | — | US | claimed |
| US-20080099249-A1 | TOOL WITH A LARGE VOLUME OF A SUPERHARD MATERIAL | SCHLUMBERGER TECHNOLOGY CORPORATION | 2008-05-01 | — | — | US | claimed |
| US-20080100124-A1 | Tool with a Large Volume of a Superhard Material | SCHLUMBERGER TECHNOLOGY CORPORATION | 2008-05-01 | — | — | US | claimed |
| US-7353893-B1 | Tool with a large volume of a superhard material | SCHLUMBERGER TECHNOLOGY CORPORATION | 2008-04-08 | — | — | US | claimed |
| US-20060094919-A1 | Isomerization catalyst and process | UOP LLC | 2006-05-04 | — | — | US | claimed |
| US-20060094592-A1 | Isomerization catalyst and process | UOP LLC | 2006-05-04 | — | — | US | claimed |
| EP-0701861-B1 | A diamond sintered body and a process for the production of the same, tools and abrasive grains using the same | SUMITOMO ELECTRIC INDUSTRIES (JP) | 2004-11-17 | — | — | EP | claimed |
| US-5912217-A | DIAMONDS AND BREAKAGE RESISTANCE, CORROSION RESISTANCE, HEAT RESISTANCE AND WEAR RESISTANCE | SUMITOMO ELECTRIC INDUSTRIES, LTD. (JP) | 1999-06-15 | — | — | US | claimed |
| EP-0701861-A2 | A diamond sintered body and a process for the production of the same, tools and abrasive grains using the same | Sumitomo Electric Industries, Ltd. (JP) | 1996-03-20 | — | — | EP | claimed |