Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALCA | P06881 | 4/20 | 0.41 |
| ▸ | MC4R | P32245 | 8/20 | 0.40 |
| ▸ | PROKR1 | Q8TCW9 | 4/20 | 0.40 |
| ▸ | MC5R | P33032 | 1/20 | 0.39 |
| ▸ | MC3R | P41968 | 1/20 | 0.39 |
| ▸ | MC1R | Q01726 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | UGCG | Q16739 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | CCR1 | P32246 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12713329 | 1.00 | CALCA (0.41) | CALCAMC4RPROKR1MC5RMC3R | |
| SCHEMBL12713318 | 0.92 | CALCA (0.41) | CALCAMC4RPROKR1MC5RMC3R | |
| SCHEMBL12713343 | 0.92 | CALCA (0.44) | CALCAPROKR1CCR1 | |
| SCHEMBL12713355 | 0.91 | CALCA (0.44) | CALCAMC4RPROKR1MC5RMC3R | |
| SCHEMBL12713177 | 0.88 | CALCA (0.46) | CALCAMC4RPROKR1MC5RMC3R | |
| SCHEMBL12713327 | 0.87 | CALCA (0.42) | CALCAMC4RMC5RMC3RMC1R | |
| SCHEMBL13132495 | 0.86 | CALCA (0.40) | CALCAMC4RMC5RMC3RMC1R | |
| SCHEMBL12713317 | 0.83 | CALCA (0.42) | CALCAMC4RPROKR1MC5RMC3R | |
| SCHEMBL12713335 | 0.83 | CALCA (0.43) | CALCAMC4RMC5RMC3RMC1R | |
| SCHEMBL12713332 | 0.83 | CALCA (0.43) | CALCAMC4RMC5RMC3RMC1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007115798-A1 | SUBSTITUTED PHENYLPIPERIDINE DERIVATIVES AS MELANOCORTIN-4 RECEPTOR MODULATORS | SANTHERA PHARMACEUTICALS (SCHWEIZ) AG (CH) | 2007-10-18 | — | — | WO | disclosed |