Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALCA | P06881 | 14/20 | 0.45 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.40 |
| ▸ | ADAMTS5 | Q9UNA0 | 2/20 | 0.40 |
| ▸ | PROKR1 | Q8TCW9 | 2/20 | 0.39 |
| ▸ | CCR1 | P32246 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12713342 | 1.00 | CALCA (0.45) | CALCAADAM17ADAMTS5PROKR1CCR1 | |
| SCHEMBL12713317 | 0.92 | CALCA (0.42) | CALCAADAM17ADAMTS5PROKR1CCR1 | |
| SCHEMBL12713343 | 0.91 | CALCA (0.44) | CALCAPROKR1CCR1 | |
| SCHEMBL12713353 | 0.90 | CALCA (0.45) | CALCAADAM17ADAMTS5 | |
| SCHEMBL12713340 | 0.87 | CALCA (0.46) | CALCAADAM17ADAMTS5CCR1 | |
| SCHEMBL12713293 | 0.86 | CALCA (0.46) | CALCACCR1 | |
| SCHEMBL12713344 | 0.84 | CALCA (0.45) | CALCAPROKR1CCR1 | |
| SCHEMBL12713171 | 0.83 | CALCA (0.46) | CALCAADAM17ADAMTS5 | |
| SCHEMBL12713318 | 0.83 | CALCA (0.41) | CALCAADAM17ADAMTS5PROKR1CCR1 | |
| SCHEMBL12713347 | 0.83 | CALCA (0.49) | CALCACCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007115798-A1 | SUBSTITUTED PHENYLPIPERIDINE DERIVATIVES AS MELANOCORTIN-4 RECEPTOR MODULATORS | SANTHERA PHARMACEUTICALS (SCHWEIZ) AG (CH) | 2007-10-18 | — | — | WO | disclosed |