Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 17/20 | 0.44 |
| ▸ | DPP7 | Q9UHL4 | 12/20 | 0.41 |
| ▸ | DPP9 | Q86TI2 | 12/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 11/20 | 0.41 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18387227 | 0.86 | IDO1 (0.42) | DPP4DPP7DPP9DPP8RIPK1 | |
| SCHEMBL14402426 | 0.84 | DPP4 (0.43) | DPP4DPP7DPP9DPP8RIPK1 | |
| SCHEMBL13849908 | 0.84 | DPP4 (0.43) | DPP4DPP7DPP9DPP8RIPK1 | |
| SCHEMBL14402710 | 0.80 | IDO1 (0.46) | HTR2AHTR2C | |
| SCHEMBL23095179 | 0.79 | NPC1 (0.38) | HTR2AHTR2C | |
| SCHEMBL8250509 | 0.79 | DPP4 (0.50) | DPP4DPP7DPP9DPP8RIPK1 | |
| SCHEMBL8282066 | 0.78 | DPP4 (0.48) | DPP4DPP7DPP9DPP8 | |
| SCHEMBL8281694 | 0.78 | DPP4 (0.48) | DPP4DPP7DPP9DPP8 | |
| SCHEMBL14402586 | 0.78 | TAAR1 (0.41) | RIPK1 | |
| SCHEMBL15178317 | 0.77 | DPP4 (0.40) | DPP4DPP7DPP9DPP8RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1847533-A1 | SIX-MEMBERED HETEROCYCLIC COMPOUND AND THE USE THEREOF | Asahi Kasei Pharma Corporation (JP) | 2007-10-24 | — | — | EP | disclosed |